University of Debrecen - Nagyértékű eszközök

Instruments

Name of the Instrument	Brief description of the Instrument	Responsible Person for the Instrument	Instrument Specification
Agilent 5975C Series GC/MSD	-	Responsible: Posta János Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Forensic Medicine E-mail: posta@med.unideb.hu	-
Agilent 6120 Quadrupole LCMS System	-	Responsible: Posta János Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Forensic Medicine E-mail: posta@med.unideb.hu	• Mass range: m/z 10–1500 • Mass accuracy: ± 0.13 u within the calibrated mass range in scan mode • Mass axis stability: Mass drift does not exceed the larger absolute value of ± 0.1 u or ± 100 ppm of measured mass over a 12 hour period at constant temperature ± 3 degrees centigrade • Scan Speed: 2500 u/s • SIM sensitivity:• ESI at 400 μL/min or APCI at 1000 μL/min • Selected ion monitoring of m/z 609.3 • Positive ionization 10 pg reserpine, 100:1 RMS (20:1 peak-to-peak) • Scan sensitivity: • ES
ABI 3130 Genetic Analyzer	4-capillary automatic fluoroscence electrophoresis unit	Phone: +36 (30) 358-7385 Other contact: Szakácsi János, szakacsi@belklinika.com, +36 303587385	4-capillary automatic fluoroscence electrophoresis unit
MICROSCOPE	https://www.spachoptics.com/BX51-DIC-FL-p/olympus-bx51-dic-fl.htm	Responsible: Sólyom Ferenc Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Pathology E-mail: sfe@med.unideb.hu Phone: +36 (52) 255-847	https://www.spachoptics.com/BX51-DIC-FL-p/olympus-bx51-dic-fl.htm
MICROSCOPE	https://www.spachoptics.com/BX51-DIC-FL-p/olympus-bx51-dic-fl.htm	Responsible: Sólyom Ferenc Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Pathology E-mail: sfe@med.unideb.hu Phone: +36 (52) 255-847	https://www.spachoptics.com/BX51-DIC-FL-p/olympus-bx51-dic-fl.htm
Mikroszkóp kamerával	https://www.spachoptics.com/BX51-DIC-FL-p/olympus-bx51-dic-fl.htm	Responsible: Sólyom Ferenc Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Pathology E-mail: sfe@med.unideb.hu Phone: +36 (52) 255-847	https://www.spachoptics.com/BX51-DIC-FL-p/olympus-bx51-dic-fl.htm
Mikroszkóp fluorescens	https://www.zeiss.com/microscopy/int/products/light-microscopes/axio-imager-for-polarized-light.html	Responsible: Sólyom Ferenc Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Pathology E-mail: sfe@med.unideb.hu Phone: +36 (52) 255-847	https://www.zeiss.com/microscopy/int/products/light-microscopes/axio-imager-for-polarized-light.html
Biorobot	https://www.qiagen.com/us/spotlight-pages/ias/qiacube-classic-resource-page/	Responsible: Sólyom Ferenc Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Pathology E-mail: sfe@med.unideb.hu Phone: +36 (52) 255-847	https://www.qiagen.com/us/spotlight-pages/ias/qiacube-classic-resource-page/
Sequencing device	https://www.roche.com/media/releases/med-cor-2012-01-17t.htm	Responsible: Sólyom Ferenc Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Pathology E-mail: sfe@med.unideb.hu Phone: +36 (52) 255-847	https://www.roche.com/media/releases/med-cor-2012-01-17t.htm
NGS Sequencing Machine	https://www.genetica.hu/miseq-rendszer	Responsible: Sólyom Ferenc Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Pathology E-mail: sfe@med.unideb.hu Phone: +36 (52) 255-847	https://www.genetica.hu/miseq-rendszer
AUTOMATIC COVER	https://www.leicabiosystems.com/histology-equipment/he-slide-stainers-special-stainers-coverslippers/leica-cv5030/	Responsible: Sólyom Ferenc Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Pathology E-mail: sfe@med.unideb.hu Phone: +36 (52) 255-847	https://www.leicabiosystems.com/histology-equipment/he-slide-stainers-special-stainers-coverslippers/leica-cv5030/
Evidence Investigator	-	Responsible: Tóth Gábor Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Laboratory Medicine E-mail: tothg@med.unideb.hu Phone: +36 (30) 360-2516	Fully automated, chemiluminescent immunoassay Analyzer
BECKMAN COULTER FC 500 FLOW CYTOMETER	The flow cytometer is an instrument for determining the light scatter, immunophenotype and DNA content of cells in suspension. Flow cytometry is an essential diagnostic method for leukaemias. The BC FC500 flow cytometer is equipped with 2 lasers (488, 635) and 4 fluorescence detectors. Analysis of 4 colours is possible.	Responsible: Tóth Gábor Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Laboratory Medicine E-mail: tothg@med.unideb.hu Phone: +36 (30) 360-2516	Power: 230V 20A Dimensions:61x90x74 cm, Weight 84 kg
ABI prism 310 Perkin Elmer Genetic Analyzer	In PCR reactions, the sample to be sequenced is labelled with fluorescently labelled dideoxy-NTPs, which result in label fragments of different sizes that are separated during capillary electrophoresis. The labelled fragment arriving at the detection window is excited by a laser and the fluorescent signal is received by a CCD camera. In fragment analysis, a dye-labelled primer is used in the PCR reaction , and the resulting labelled fragments can be detected. Size standard can be added to perform the measurement.	Responsible: Tóth Gábor Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Laboratory Medicine E-mail: tothg@med.unideb.hu Phone: +36 (30) 360-2516	The device is a 1 capillary system which can be used with reagents produced by the manufacturer. 50 cm capillary , POP-6 polymer is used. Size: 55.88cmx60,96cmx86.36cm.Weight 94,5 kg.48 automatic single sample dispenser holder available.Max. 950bp readability.220 V voltage supply can be operated with power supply Sample volume min. 10uL.
ABI prism 310 Genetic Analyzer	In PCR reactions, fluorescently labelled dideoxy-NTPs are used to label the sample to be sequenced, and the chain termination results in label fragments of different sizes, which are separated during capillary electrophoresis. The labelled fragment arriving at the detection window is excited by a laser and the fluorescent signal is received by a CCD camera. In fragment analysis, a dye-labelled primer is used in the PCR reaction , and the resulting labelled fragments can be detected. Size standard can be added to perform the measurement.	Responsible: Tóth Gábor Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Laboratory Medicine E-mail: tothg@med.unideb.hu Phone: +36 (30) 360-2516	The device is a 1 capillary system which can be used with reagents produced by the manufacturer. 50 cm capillary , POP-6 polymer is used. Size: 55.88cmx60,96cmx86.36cm.Weight 94,5 kg.It has 48 automatic single sample dispenser holders.Max. 950bp readability.220 V voltage supply operable Sample volume min. 10uL.
FACS CANTO II FLOW CYTOMETER	The flow cytometer is an instrument for determining the light scatter, immunophenotype and DNA content of cells in suspension. Flow cytometry is an essential diagnostic method for leukaemias. The FACS CANTO II flow cytometer is equipped with 3 lasers (488, 633, 405 nm) and 8 fluorescence detectors. 8 colours can be analysed.	Responsible: Tóth Gábor Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Laboratory Medicine E-mail: tothg@med.unideb.hu Phone: +36 (30) 360-2516	Power: 230V, 16 A Size: 61x91x64 cm, Weight 145 kg
FACS CALIBUR FLOW CYTOMETER	The flow cytometer is an instrument for determining the light scatter, immunophenotype and DNA content of cells in suspension. Flow cytometry is an essential diagnostic method for leukaemias.________ The BD FACS Calibur flow cytometer is equipped with 2 lasers (488, 633 nm) and 4 fluorescence detectors. Analysis of 4 colours is possible.	Responsible: Tóth Gábor Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Laboratory Medicine E-mail: tothg@med.unideb.hu Phone: +36 (30) 360-2516	Power 230V, 20A, Size:91x61x67 cm, Weight:109 kg
NAVIOS FLOW CYTOMETER	The flow cytometer is an instrument for determining the light scatter, immunophenotype and DNA content of cells in suspension. Flow cytometry is an essential diagnostic method for leukaemias. The Navios flow cytometer is equipped with 3 lasers (488, 638, 405 nm) and 10 fluorescence detectors. 10 colours can be analysed.	Responsible: Tóth Gábor Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Laboratory Medicine E-mail: tothg@med.unideb.hu Phone: +36 (30) 360-2516	Power: 230V, 16A size: 96x61x70 cm, weight: 104 kg.
Light Cycler 480 Real time	The instrument is designed to run fluorescent real-time PCR.	Responsible: Tóth Gábor Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Laboratory Medicine E-mail: tothg@med.unideb.hu Phone: +36 (30) 360-2516	Power: 230 V 10 A, _Size 60x60x 54 cm , weight
High Pressure Biner Gradiens System_	Adjustable pressure and flow rate, computer control, sample evaluation, flexible set-up	Responsible: Tóth Gábor Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Laboratory Medicine E-mail: tothg@med.unideb.hu Phone: +36 (30) 360-2516	Power: 1500 W, size: 80x_60x 60 cm_weight : 50 kg
3130 Genetic Analyzer	In PCR reactions, the sample to be sequenced is labelled with fluorescently labelled dideoxy-NTPs, which result in label fragments of different sizes that are separated during capillary electrophoresis. The labelled fragment arriving at the detection window is excited by a laser and the fluorescent signal is received by a CCD camera. In fragment analysis, a dye-labelled primer is used in the PCR reaction , and the resulting labelled fragments can be detected. Size standard can be added to perform the measurement.	Responsible: Tóth Gábor Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Laboratory Medicine E-mail: tothg@med.unideb.hu Phone: +36 (30) 360-2516	The device is a 4 capillary system which can be used with reagents produced by the manufacturer. 36 cm capillary , POP-7 polymer is used. Size: 55cmx81cmx149cm.Weight 130 kg.Compatible with 96-platen, 2 plate holders.Max. Max. readability 950bp.230-240 V voltage can be operated with a ballast _Sample volume min. 10uL.
QIACube	It is compatible with a variety of QIAGEN DNA, RNA and protein isolation kits based on silica membrane spin column technology. Designed for simultaneous isolation of 1-12 samples. The isolated nucleic acids can then be submitted for sequence analysis and the isolated proteins for proteomic analysis.	Responsible: Tóth Gábor Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Laboratory Medicine E-mail: tothg@med.unideb.hu Phone: +36 (30) 360-2516	Voltage requirement 220V.It has a built-in 12-sample centrifuge and thermo shaker.Built-in screen control, program installation via USB port. Internal UV lamp. Closed system automatic, can be operated with manufacturer's kits and disposable media. Suitable for nucleic acid isolation using the silica column technique.
ZEISS AXIOPLAN MICROSCOPE	Equipped with a camera and computer image processing. Variable magnification, colour filters, Halogen and mercury vapour light sources. List of measurement options (min. 5, max. 10): analysis of cells, chromosomes, tissues. Autoantibody diagnostics; indirect immunofluorescence studies	Responsible: Tóth Gábor Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Laboratory Medicine E-mail: tothg@med.unideb.hu Phone: +36 (30) 360-2516	Power: 200 W, weight 9 kg, size: 50x49x 31cm
Mikroscop	10-20-40-63 HI with Plan-apochromatic lenses	Responsible: Torzsa Róbert Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Medical Microbiology E-mail: torzsa.robert@med.unideb.hu Phone: +36 (52) 411-717/50124	Fluorescence microscope
ETI MAX 3000	Automatic ELISA reader; dilutes samples, pipettes, adds reagents, incubates and weighs.	Responsible: Tóth Gábor Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Laboratory Medicine E-mail: tothg@med.unideb.hu Phone: +36 (30) 360-2516	Size :112x 76x100 cm, weight: 120 kg, power: 230 V, 10 A, measuring wavelength 400-700 nm
Elisa automata	Only the maintenance company can manage the control	Responsible: Torzsa Róbert Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Medical Microbiology E-mail: torzsa.robert@med.unideb.hu Phone: +36 (52) 411-717/50124	CE-IVD ELISA automated
PCR set	4 channels + ROX passive refernce	Responsible: Torzsa Róbert Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Medical Microbiology E-mail: torzsa.robert@med.unideb.hu Phone: +36 (52) 411-717/50124	CE-IVD and research real-time PCR
Anaerobic workstation	N2/H2 inert gas	Responsible: Torzsa Róbert Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Medical Microbiology E-mail: torzsa.robert@med.unideb.hu Phone: +36 (52) 411-717/50124	anaerobic workstation
Mass	Matrix assisted laser dissipation - time-of-flight mass spectrometer	Responsible: Torzsa Róbert Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Medical Microbiology E-mail: torzsa.robert@med.unideb.hu Phone: +36 (52) 411-717/50124	MALDI-TOF matrix-assisted laser dissociation -time of flight mass spectrometry
miniPET2 small animal PET scanner	Mouse and rat PET scanner	Responsible: Dr. Balkay László Organizational unit: University of Debrecen; Faculty of Medicine; Institute of Medical Imaging; Department of Nuclear Medicine and Translational Imaging E-mail: balkay.laszlo@med.unideb.hu Phone: +36 (52) 411-717/51445	radial FOV – 190 mm, axial FOV – 50 mm, sensitivity - 1.37%, radial spatial resolution – 1.57 mm
Liquid chromatograph Acquity UPLC	Ultra high pressure liquid chromatograph with autosampler, column manager, diode array UV and radioactivity detectors	Responsible: Szikra Dezső Péter Organizational unit: University of Debrecen; Faculty of Medicine; Institute of Medical Imaging; Department of Nuclear Medicine and Translational Imaging E-mail: szikra.dezso@med.unideb.hu Phone: +36 (52) 512-900/56194	The Waters® ACQUITY UPLC® I-Class System’s holistic design is targeted for investigative analysis where maximized peak capacity, throughput, and sensitivity are critical and is perfectly suited for running any MS based applications. The system is comprised of a Binary Solvent Manager (BSM) and a Sample Manager with Flow-Through Needle (SM-FTN); this configuration offers excellent carryover performance. The ACQUITY UPLC I-Class System is available with a choice of column management options.
Radiation monitoring system	Monitoring activity emissions during production at radio farms	Responsible: Dr. Balkay László Organizational unit: University of Debrecen; Faculty of Medicine; Institute of Medical Imaging; Department of Nuclear Medicine and Translational Imaging E-mail: balkay.laszlo@med.unideb.hu Phone: +36 (52) 411-717/51445	Netview 32, v3.18
CIKLOTRON	GE PETtrace particle accelerator, specially designed for the production of PET isotopes. It is capable of accelerating both protons (16.5MeV) and deuterons (8.5MeV) and thus triggering a nuclear reaction in the target. It is mainly used to produce 18F (from 18O enriched water) which is either incorporated into human diagnostic preparations on a hot cell panel in the pharmaceutical clean room or used to produce experimental compounds on another hot cell panel for scientific research. We can also produce 13N, 11C and 44Sc in our solid target.	Responsible: Várhalminé Németh Enikő Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Department of Medical Imaging; Nuclear Medicine E-mail: nemeth.eniko@med.unideb.hu Phone: +36 (52) 255-510/51701	-
Leica Cryomacrotome CM3600	The Leica CM3600 frozen section is designed for making large surface sections. The equipment is designed to produce specialised whole body sections from small laboratory animals. The incisor can be operated manually, but it is also possible to perform a predefined whole section protocol under computer control. Individual sections can be transferred to both plastic tapes and glass slides for the determination of radioactivity distributions obtained in digital format or for other processing of a different nature.	Responsible: Nagy Tamás Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Department of Medical Imaging; Nuclear Medicine E-mail: nagy.tamas@med.unideb.hu Phone: +36 (52) 255-510/56853	Thickness of sections: 1-200um, length of sections: 0-450mm, total vertical range of sections 70mm, maximum sample size 45015070mm
SMC DOUBLE 1/70 DMC 1/70 hot cell	The hot box is a large, cast, lead-brick-encased device mounted on a reinforced slab, which cannot be moved. It is equipped with its own ventilation system, the air can be extracted from its interior and collected separately if necessary. It can be used for controlled work with radioactive isotopes, mainly gamma rays. It currently houses experimental radioactive signalling equipment	Responsible: Várhalminé Németh Enikő Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Department of Medical Imaging; Nuclear Medicine E-mail: nemeth.eniko@med.unideb.hu Phone: +36 (52) 255-510/51701	-
11C Synthesis Module	11C isotopic labelling equipment.	Responsible: Várhalminé Németh Enikő Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Department of Medical Imaging; Nuclear Medicine E-mail: nemeth.eniko@med.unideb.hu Phone: +36 (52) 255-510/51701	Synthesis panel equipped with flow and pressure gauges, heated cooled reactor, temperature and activity indicators.
Methylation reactor	-	Responsible: Várhalminé Németh Enikő Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Department of Medical Imaging; Nuclear Medicine E-mail: nemeth.eniko@med.unideb.hu Phone: +36 (52) 255-510/51701	Stainless steel heated, cooled reactor body, in which a glass reactor can be placed to perform the synthesis.
SYNTHESIS HOT CELL	Enclosed workplace with lead shielding and extraction to facilitate work with gamma-emitting isotopes.	Responsible: Várhalminé Németh Enikő Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Department of Medical Imaging; Nuclear Medicine E-mail: nemeth.eniko@med.unideb.hu Phone: +36 (52) 255-510/51701	Enclosed workplace with lead shielding and fume extraction
HOT CELL	Enclosed workplace with lead shielding and extraction to facilitate work with gamma-emitting isotopes.	Responsible: Várhalminé Németh Enikő Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Department of Medical Imaging; Nuclear Medicine E-mail: nemeth.eniko@med.unideb.hu Phone: +36 (52) 255-510/51701	Enclosed workplace built of lead bricks with extraction.
Synthesis_Module	Process-driven synthesis panel for 18F isotope labelling. _With heated, cooled reactor, activity indicators._Must be housed in a lead shielded enclosure for safe operation.	Responsible: Várhalminé Németh Enikő Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Department of Medical Imaging; Nuclear Medicine E-mail: nemeth.eniko@med.unideb.hu Phone: +36 (52) 255-510/51701	-
HPLC system	For the quality control of radiopharmaceuticals for the performance of chromatographic tests	Responsible: Várhalminé Németh Enikő Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Department of Medical Imaging; Nuclear Medicine E-mail: nemeth.eniko@med.unideb.hu Phone: +36 (52) 255-510/51701	UV detection, radioactivity detector, automatic injector, eluent transport unit, low pressure eluent mixing unit, degasser
can be produced by 18F-FET GRP	Automated equipment used to produce the radiopharmaceutical used in PET/CT studies - 18F-FET. It is located in a hot box in the clean room. It can be used to produce 18F-FETs, as provided for in the Institute's pharmaceutical manufacturing licence, and also to produce research pharmacons	Responsible: Várhalminé Németh Enikő Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Department of Medical Imaging; Nuclear Medicine E-mail: nemeth.eniko@med.unideb.hu Phone: +36 (52) 255-510/51701	-
Hot cabin	Not for measurement, but for working with gamma-ray isotopes. By placing automated equipment in its interior.	Responsible: Várhalminé Németh Enikő Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Department of Medical Imaging; Nuclear Medicine E-mail: nemeth.eniko@med.unideb.hu Phone: +36 (52) 255-510/51701	A hot cabin is a device mounted on a reinforced slab and surrounded by lead bricks with a large cast mass, which makes it immovable. Air can be extracted from its interior and collected separately if necessary. It can be used for controlled work with radioactive isotopes, mainly gamma rays. It is currently used for GMP pharmaceutical production - radioactive
Hot Cabin	A hot cabin is a device mounted on a reinforced slab and surrounded by lead bricks with a large cast mass, which makes it immovable. Air can be extracted from its interior and collected separately if necessary. It can be used for controlled work with radioactive isotopes, mainly gamma rays. It is currently used for GMP pharmaceutical production - radioactive	Responsible: Várhalminé Németh Enikő Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Department of Medical Imaging; Nuclear Medicine E-mail: nemeth.eniko@med.unideb.hu Phone: +36 (52) 255-510/51701	-
Hot cabin	A hot cabin is a device mounted on a reinforced slab and surrounded by lead bricks with a large cast mass, which makes it immovable. Air can be extracted from its interior and collected separately if necessary. It can be used for controlled work with radioactive isotopes, mainly gamma rays. It is currently used for GMP pharmaceutical production - radioactive	Responsible: Várhalminé Németh Enikő Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Department of Medical Imaging; Nuclear Medicine E-mail: nemeth.eniko@med.unideb.hu Phone: +36 (52) 255-510/51701	-
Hot cabin	A hot cabin is a device mounted on a reinforced slab and surrounded by lead bricks with a large cast mass, which makes it immovable. Air can be extracted from its interior and collected separately if necessary. It can be used for controlled work with radioactive isotopes, mainly gamma rays. It is currently used for GMP pharmaceutical production - radioactive	Responsible: Várhalminé Németh Enikő Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Department of Medical Imaging; Nuclear Medicine E-mail: nemeth.eniko@med.unideb.hu Phone: +36 (52) 255-510/51701	-
SYNTHESIS MODEL FX-FDG	The most commonly used radiopharmaceutical in PET/CT studies - 18F-FDG - is an automated device for the production of the radiopharmaceutical. It is located in a hot chamber in the clean room.It can only be used to produce FDG as specified in the Institute's drug manufacturing licence and cannot be used for any other purpose.	Responsible: Várhalminé Németh Enikő Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Department of Medical Imaging; Nuclear Medicine E-mail: nemeth.eniko@med.unideb.hu Phone: +36 (52) 255-510/51701	-
Download booth	A forró fülke egy megerősített födémre elhelyezett, nagy öntömegű, ólom téglákkal körberakott eszköz, mely ezáltal nem mozdítható. A belső teréből a levegő elszívható és szükség esetén külön gyűjthető. Radioaktív, elsősorban gammasugárzó izotópokkal való kontrollált munka végezhető benne. Jelenleg GMP gyógyszergyártás - radioaktív – során készült humán diagnosztikai terméket osztunk el ebben a speciális forrófülkében	Responsible: Várhalminé Németh Enikő Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Department of Medical Imaging; Nuclear Medicine E-mail: nemeth.eniko@med.unideb.hu Phone: +36 (52) 255-510/51701	-
Download booth	A hot cabin is a device mounted on a reinforced slab and surrounded by lead bricks with a large cast mass, which makes it immovable. Air can be extracted from its interior and collected separately if necessary. It can be used for controlled work with radioactive isotopes, mainly gamma rays. Currently, GMP pharmaceuticals - radioactive - human diagnostic products are dispensed in this special hot chamber	Responsible: Várhalminé Németh Enikő Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Department of Medical Imaging; Nuclear Medicine E-mail: nemeth.eniko@med.unideb.hu Phone: +36 (52) 255-510/51701	-
DOUBLE RADIO FLUORING UNIT	A PET/CT vizsgálatok során leggyakrabban használt radiogyógyszer – 18F-FDG- előállítására használt autómata berendezés. A tisztatérben található forrófülkében van elhelyezve.Kizárólag az intézet gyógyszergyártási engedélyében foglalt módon gyártható vele FDG, másra nem használható	Responsible: Várhalminé Németh Enikő Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Department of Medical Imaging; Nuclear Medicine E-mail: nemeth.eniko@med.unideb.hu Phone: +36 (52) 255-510/51701	-
SYNTHESIS MODUL_TRACERLAB-FX FDG SYSTEM	A PET/CT vizsgálatok során leggyakrabban használt radiogyógyszer – 18F-FDG- előállítására használt autómata berendezés. A tisztatérben található forrófülkében van elhelyezve.Kizárólag az intézet gyógyszergyártási engedélyében foglalt módon gyártható vele FDG, másra nem használható_	Responsible: Várhalminé Németh Enikő Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Department of Medical Imaging; Nuclear Medicine E-mail: nemeth.eniko@med.unideb.hu Phone: +36 (52) 255-510/51701	-
Autoklav	The equipment is suitable for sterilising heat-tolerant instruments, instruments and dressings.	Responsible: Horváth Éva Organizational unit: Klinikai Központ; Fogorvosi járó- és fekvőbeteg alap- és szakellátó szolgálat E-mail: horvath.eva@dental.unideb.hu Phone: +36 (70) 341-0134	Central steam sterilizer with saturated pressurized steam supply.
OPTIMA LE80K ULTRACENTRIFUGA	max. speed 80,000 rpm, fast separation, accepts a wide range of rotors and tube types	Responsible: Dr. Tóth Judit Organizational unit: University of Debrecen; Faculty of Medicine; Institute of Medical Imaging; Department of Radiology and Imaging Science E-mail: tothjudit@med.unideb.hu Phone: +36 (70) 214-1475	(120.7 cm x 94.0 cm x 67.3 cm), 465 kg, speed: 1000 rpm to 80 000 rpm in increments of 100 rpm, loading time: up to 99 hours and 59 minutes, temperature: 0-40 C, programs. Standard, programmed or delayed start; max. 9 programs can be saved
ABI PRISM 310	Sequencing works on the principle of capillary electrophoresis. Samples are transferred from the sample holder to the capillary by an automated system, ensuring reproducible and consistent measurements. Samples are labelled with fluorescently labelled dideoxy-NTPs in a PCR reaction, which, due to chain termination, produces label fragments of different sizes that are separated during capillary electrophoresis. The label fragment arriving at the detection window is excited by a laser and the fluorescent signal is received by a CCD camera. Full software control and evaluation (310 Data Collection Software, GeneMapper®, GeneMapper® ID, Sequencing Analysis, SeqScape®)	Responsible: Dr. Tóth Judit Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Clinics; Department of Oncology E-mail: judit.toth@med.unideb.hu Phone: +36 (70) 214-1475 Other contact: deoecvbkl@gmail.com	detection with CCD camera, 525 - 650 nm range, optics: 10 mW argon ion laser, electrophoresis power supply (100 V - 15 kV), gel pump (pressure < 1800 psi), sample holder (48 or 96 samples), capillary temperature (room temperature - 60 ˚C)
SYNERGY4 plate reader	-	Responsible: Dr. Tóth Judit Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Clinics; Department of Oncology E-mail: judit.toth@med.unideb.hu Phone: +36 (70) 214-1475 Other contact: deoecvbkl@gmail.com	Temperature range: 4°C - 50°C ± 0.5°C at 37°C, built-in shaking, insertable plates (1 - 384-well plate) Absorbance measurement: light source: SQ Xenon Flash, wavelength range (200 - 999nm, can be raised as 1nm), monochromator, measuring range: 0 - 4.0 OD, resolution: 0.001 OD Fluorescence measurement: wavelength range (200 - 700 nm), Double grating monochromators (Top) and, deep blocking bandpass filters / dichroic mirrors (Top/Bottom), detection: Multi Label
Plate Reader	The NovoStar plate reader can measure in three measurement modes (absorbance, fluorescence, luminescence), lower and upper reading mode. It has a built-in pipettor and two reagent injectors, allowing a significant degree of automation of the measurement. The internal temperature of the instrument can be adjusted up to 45°C and a gas cylinder can be connected to the instrument to supply a suitable gas mixture to the measuring chamber to ensure cell survival. Filters are provided to ensure the correct wavelengths.	Responsible: Dr. Tóth Attila Organizational unit: University of Debrecen; Faculty of Medicine; Institute of Cardiology; Division of Clinical Physiology E-mail: atitoth@med.unideb.hu Phone: +06 (52) 411-717/56274	1 measuring plate, 1 reagent plate, 1 pipettor, 2 injectors, internal temperature adjustable up to 45°C, excitation and emission side filter discs with 8-8 positions, xenon flashlight light source, kinetic and end-point measurements, multi-directional plate coating.
Asymmetric Flow Field Flow Fractioner, AF4	The instrument is a combination of a Shimadzu UFLC and a Postnova AF4, which can be used separately. The AF4 is a special principle chromatography instrument that separates the sample by size using countercurrent without significant dilution of the sample (as opposed to gel chromatography). In terms of size resolution, it can be used for separations from a few thousand Da molecular size to particles/cell sizes of a few 10 micrometres. It is a very fluid-intensive instrument. The UFLC has a quaternary pump. The instrument has a diode array detector and a built-in sample feeder and fraction collector. The separation is based on the fact that the sample is prevented from advancing by a transverse fluid flow, the effect of which is proportional to the size of the components in the sample.	Responsible: Dr. Tóth Attila Organizational unit: University of Debrecen; Faculty of Medicine; Institute of Cardiology; Division of Clinical Physiology E-mail: atitoth@med.unideb.hu Phone: +06 (52) 411-717/56274	The AF4 consists of PN7140 solvent organizer, PN750 degasser, 2 PN1130 isocratic pumps, AF2000 countercurrent module, PN5300 autosampler, PN4020 temperature control module (for AF2000 module temperature control). UFLC parts: DGU-20A degasser, LC-20AD pump. Common components: CBM-20A SPD-M20A detector, FRC-10A fraction collector.
Echocardiographic system	The GE Healthcare Vivid E9 Cardiac Ultrasound is specifically designed for 4D imaging. We currently have a TTE transducer for human and small animal studies.	Responsible: Dr. Tóth Attila Organizational unit: University of Debrecen; Faculty of Medicine; Institute of Cardiology; Division of Clinical Physiology E-mail: atitoth@med.unideb.hu Phone: +06 (52) 411-717/56274	Monitor: 17" HD LCD, 1280*1024 resolution, max. examination depth: 30 cm, min. examination depth: 0-2cm, 2D, M-mode, M-color flow mode, anatomical M-mode, trapezoidal mode, pulsed Doppler mode, HD flow mode, SCE doppler, tissue doppler imaging, live 3D echo, panoramic imaging, contrast imaging,
FACSCalibur FLOW CYTOMETER	White blood cell analysis - immunophenotyping, cell activation assays, immune cell differentiation assays, determination of immune cells producing different cytokines by intracellular labelling Apoptotic cell isolation, cell viability assay	Responsible: Szabó Krisztina Organizational unit: University of Debrecen; Faculty of Medicine; Department of Internal Medicine; Division of Clinical Immunology E-mail: krisztinaszabo@med.unideb.hu Phone: +36 (52) 255-218/51100 Other contact: krsztn.szabo@gmail.com	Ar-ion laser (488nm, 15mW) red diode laser (635nm) FSC, SSC and fluorescence detectors (PMT1-PMT4 / FL1-FL4)
CYTOMICSTM FC500 FLOW CYTOMETER	White blood cell analysis - immunophenotyping, cell activation assays, immune cell differentiation assays, determination of immune cells producing different cytokines by intracellular labelling Apoptotic cell isolation, cell viability assay	Responsible: Szabó Krisztina Organizational unit: University of Debrecen; Faculty of Medicine; Department of Internal Medicine; Division of Clinical Immunology E-mail: krisztinaszabo@med.unideb.hu Phone: +36 (52) 255-218/51100 Other contact: krsztn.szabo@gmail.com	Ar-ion laser (488nm, 20mW) red diode laser (635nm, 25mW) FSC, SSC and fluorescence detectors (PMT1-PMT5 / FL1-FL5)
Autoclave (SAR 6.6 12-2V)	Steam sterilizer used for sterilization. Detailed instructions for its use can be found in the publication "Information on sterilisation" published by the Department of Disinfection of the National Centre for Epidemiology (Dr. Zoltán Pechó, Dr. Márta Milassin Budapest, 2010).	Responsible: Nábrádi Tibor Zsoltné Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Organizational units related to the health care activities; Clinical Centre Vice President for Coordination; Clinical Centre Operative Directorate; Department of Hospital Hygiene E-mail: ntiborne@med.unideb.hu Phone: +36 (52) 255-795/56457	230/400 V 2,5 KW; Steam max:2, 75 bar; Air max: 7-9 bar; V= 713 l
Autoclave (SAR 6.6 12-2V)	Steam sterilizer used for sterilization. Detailed instructions for its use can be found in the publication "Information on sterilisation" published by the Department of Disinfection of the National Centre for Epidemiology (Dr. Zoltán Pechó, Dr. Márta Milassin Budapest, 2010).	Responsible: Nábrádi Tibor Zsoltné Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Organizational units related to the health care activities; Clinical Centre Vice President for Coordination; Clinical Centre Operative Directorate; Department of Hospital Hygiene E-mail: ntiborne@med.unideb.hu Phone: +36 (52) 255-795/56457	(max 500 characters): 230/400 V 2,5 KW; Steam max:2, 75 bar; Air max: 7-9 bar; V= 713 l
Autoclave (SAR 6.6 12-2V)	Steam sterilizer used for sterilization. Detailed instructions for its use can be found in the publication "Information on sterilisation" published by the Department of Disinfection of the National Centre for Epidemiology (Dr. Zoltán Pechó, Dr. Márta Milassin Budapest, 2010).	Responsible: Nábrádi Tibor Zsoltné Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Organizational units related to the health care activities; Clinical Centre Vice President for Coordination; Clinical Centre Operative Directorate; Department of Hospital Hygiene E-mail: ntiborne@med.unideb.hu Phone: +36 (52) 255-795/56457	230/400 V 2,5 KW; Steam max:2, 75 bar; Air max: 7-9 bar; V= 713 l
Sterilizer with 2 doors (V Pro Max)	Plasma sterilizer used for sterilization purposes. Detailed instructions for its use can be found in the publication "Information on sterilisation" published by the Department of Disinfection of the National Centre for Epidemiology (Dr. Zoltán Pechó, Dr. Márta Milassin Budapest, 2010).	Responsible: Nábrádi Tibor Zsoltné Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Organizational units related to the health care activities; Clinical Centre Vice President for Coordination; Clinical Centre Operative Directorate; Department of Hospital Hygiene E-mail: ntiborne@med.unideb.hu Phone: +36 (52) 255-795/56457	-
Sterilizer with 2 doors (V Pro Max)	Plasma sterilizer used for sterilization purposes. Detailed instructions for its use can be found in the publication "Information on sterilisation" published by the Department of Disinfection of the National Centre for Epidemiology (Dr. Zoltán Pechó, Dr. Márta Milassin Budapest, 2010).	Responsible: Nábrádi Tibor Zsoltné Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Organizational units related to the health care activities; Clinical Centre Vice President for Coordination; Clinical Centre Operative Directorate; Department of Hospital Hygiene E-mail: ntiborne@med.unideb.hu Phone: +36 (52) 255-795/56457	-
Sterilizer with 2 doors (V Pro Max)	Plasma sterilizer used for sterilization purposes. Detailed instructions for its use can be found in the publication "Information on sterilisation" published by the Department of Disinfection of the National Centre for Epidemiology (Dr. Zoltán Pechó, Dr. Márta Milassin Budapest, 2010).	Responsible: Nábrádi Tibor Zsoltné Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Organizational units related to the health care activities; Clinical Centre Vice President for Coordination; Clinical Centre Operative Directorate; Department of Hospital Hygiene E-mail: ntiborne@med.unideb.hu Phone: +36 (52) 255-795/56457	-
PROTEIN CHROMATOGRAPH / AKTA FPLC	A high-pressure chromatography system for the rapid liquid chromatographic separation (FPLC) of proteins using different columns. The apparatus is equipped with two pump systems. The flow rate is variable from 0,1 ml/min to 10 ml/min. The instrument is equipped with on-line UV and conductivity detector, fraction collector. Different injection loops are available for sample application. Gradient elution is provided by a mixer. The operation is fully automatic, using UNICORN 4.11 software. One of the main disadvantages of the instrument is that it cannot be used at 4°C.	Responsible: Haramura Gizella Organizational unit: University of Debrecen; Faculty of Medicine; Institute of Laboratory Medicine; Division of Clinical Laboratory Science E-mail: haramura@med.unideb.hu	- two pump system - flow rate: 0.1 ml/min-10 ml/min - column connection - 254 nm, 280 nm, 214 nm filters - fraction collector - UNICORN 4.11 software
ANALYZER FOR BIOMOLECULAR INTERACTIONS	The Biacore X is a semi-automatic, highly sensitive device using SPR (surface plasmon resonance) technology. Surface plasmons are electron density waves associated with the movement of conduction electrons at the interface of a metal and a dielectric. The plasmons are excited by light, the energy of which is transferred to the electron density wave. Plasmon excitation occurs at a given angle of incidence of light. The value of the angle of incidence corresponding to the resonance depends on the refractive index of the medium in contact with the other side of the illuminated metal layer. To investigate the interaction of the molecules in question, one of them is attached to the surface of a sensor chip, while its interacting partner is flowed in a buffer solution in contact with the metal. When the interaction occurs, the refractive index of the layer in contact with the surface changes. This change is detected by the device through a shift in the resonance angle.	Responsible: dr. Pénzes-Daku Krisztina Organizational unit: University of Debrecen; Faculty of Medicine; Institute of Laboratory Medicine; Division of Clinical Laboratory Science E-mail: kpenzes@med.unideb.hu	- Sensor chip split into 2 cells by IFC - Compatibility with GE Healthcare and Xantec chips - Manual sample injection - Light source: 800 nm wavelength light emitting diode - Semi-cylindrical prism ensures full reflection of incident light - Light is focused by a lens focusing system
AUTOMATED GENETIC ANALYZER / / AVANT 3130 ABI PRISM	The automatic 4-capillary sequencer is suitable for nucleic acid analysis by the Sanger method. It is based on the principle of capillary electrophoresis with 4 capillaries for fast and efficient operation. It is also suitable for fluorescent fragment analysis in addition to nucleic acid sequencing. It can also be used for the analysis of insertions and deletions involving larger gene sequences.	Responsible: Szabó Zsuzsanna Organizational unit: University of Debrecen; Faculty of Medicine; Institute of Laboratory Medicine; Division of Clinical Laboratory Science E-mail: zsuzska001@gmail.com	Analysis Software: GeneMapper Software v4.1, Sequencing Analysis v5.4, Foundation Data Collection v3.1; Operating System: Microsoft windows 7; Capillary Number: 4; Capillary Length: 36 cm; Polymers: POP-7; Polymer Consumption: 960 samples/7000µL; Sample Number: 96; Sample Volume:>10µL; Read Length: 950bp
PCR INSTRUMENT / LIGHT CYCLER	The LightCycler (Roche Diagnostics GmbH, Mannheim, Germany) is a thermocycler with a capillary reservoir, containing the capillaries, heating and cooling elements for rapid temperature changes during the reactions. The optimal sample capacity of the capillaries is 15-20 μl. The instrument uses a xenon reflector lamp for excitation and a CCD camera for detection. The LightCycler system includes a computer with software.	Responsible: Gindele Réka Organizational unit: University of Debrecen; Faculty of Medicine; Institute of Laboratory Medicine; Division of Clinical Laboratory Science E-mail: gindele.reka@med.unideb.hu	- excitation source: xenon lamp - Extinction filters: 440,465,498,533,618 nm (System II) - detection: CCD camera - detection filters: 488,510,580,610,640,660 nm (System II) - measurement mode: real-time, online - run time: <40 minutes
CLINICAL CHEMISTRY AUTOMATED ANALYZER / MODULAR P800	A fully automated software-driven system for clinical chemistry and immunoassay analysis. The instrument is a high-throughput clinical chemistry analyser. Measurement is spectrophotometric and is suitable for both end-point and kinetic measurements. Enzyme and substrate determinations can be performed on the instrument, which is also equipped with open channels so that other manufacturer's (or in-house prepared) reagents can be used for measurements. It is fully automated, modular, computerised, handles serum/plasma, urine, CSF and supernatant sample types, and performs in vitro quantitative and qualitative assays on a wide spectrum of analytes. It performs potentiometric and photometric analyses in modules D and P, electrochemiluminescence in module E and ion-selective analyses in module ISE.	Responsible: Molnár Éva Organizational unit: University of Debrecen; Faculty of Medicine; Institute of Laboratory Medicine; Division of Clinical Laboratory Science E-mail: molnare@med.unideb.hu Other contact: meva77@gmail.com	Automated spectrophotometric analyser. It consists of six types of hardware units: control unit, central unit, ISE module, D module, P module and E module. It can be used 24 hours a day. Measurement: 800 tests/hour. Water consumption: 50L/H.
CALORIMETER 2000 BASIC VERSION	The instrument is suitable for the calorimetric determination of the heat of combustion of various materials.	Responsible: Szatmári Imre Organizational unit: Agrár Kutatóintézetek és Tangazdaság; Karcagi Kutatóintézet (KKI); Központi Laboratórium E-mail: szatmari@agr.unideb.hu Phone: +06 (59) 500-363/109	-
ATOMABSORPTION SPECTROMETER, THERMO iCE 3500	Atomic absorption apparatus with flame, graphite and hydride generator	Responsible: Szatmári Imre Organizational unit: Agrár Kutatóintézetek és Tangazdaság; Karcagi Kutatóintézet (KKI); Központi Laboratórium E-mail: szatmari@agr.unideb.hu Phone: +06 (59) 500-363/109	Atomic absorption apparatus with flame, graphite and hydride generator
HITACHI TM3030 DESKTOP ELECTRON MICROSCOPE	HITACHI TM3030 desktop electron microscope with integrated Quantax 70 microanalytical system Scanning electron microscope with adjustable magnification (15-30000x), 2x and 4x digital zoom. The instrument is equipped with four segmented backscattered detectors and four separate amplifier modules. Brightness, contrast and focus adjustment are automatic with manual override. Sample size: 70 mm diameter, 50 mm height, movement: 35 mm x 35 mm. EDX interface digital beam steering allows for elemental imaging. Control: separate computer with USB connection. Save images in multiple formats, max. resolution 1280 x 960 pixels. Replaceable pre-centered tungsten cathode. Oil-free vacuum system. Requires single phase 230 V electrical supply. Microanalytical system: detectable elements: (5)B-(95)Am. Automatic element identification, quantitative analysis without standard.	Responsible: Magyarné Tábori Katalin Organizational unit: University of Debrecen; Institutes for Agricultural Research and Educational Farm; Research Institute of Nyíregyháza; Basic and Applied Research Unit of Nyíregyháza; Department of Plant Biotechnology and Plant Breeding E-mail: mtaborik@freemail.hu Phone: +36 (42) 594-300	Scanning electron microscope, magnification 15x - 30000x. The electron gun type is a pre-centered tungsten cathode, the detector is a four-segment high sensitivity backscattered electron detector. Start, brightness and contrast adjustment are automatic. The vacuum system includes a vacuum pump and a turbomolecular pump. The stage is motorised. The microscope is equipped with an X-ray analysis system for quantitative and qualitative analysis of elements from boron to americium.
Equipments for measuring chlorophill fluorescence, photosynthesis	The portable instruments can be used to study the physiological state of experimental field plots and in vitro plants by measuring the intensity of the building processes (photosynthesis) and the activity of photosynthetic pigments (fluorescence).	Responsible: Mendlerné Drienyovszki Nóra Organizational unit: University of Debrecen; Institutes for Agricultural Research and Educational Farm; Research Institute of Nyíregyháza; Basic and Applied Research Unit of Nyíregyháza; Department of Plant Biotechnology and Plant Breeding E-mail: mendlerne@agr.unideb.hu Phone: +36 (42) 594-300	The LCpro-SD is designed for field use and can run continuously for 4-16 hours, depending on the functions used. Its purpose is to measure and monitor the leaf environment in the chamber and to calculate the photosynthetic activity of the leaf. It calculates the assimilation and transpiration rates continuously over a complete analysis cycle of 16 to 20 seconds, based on the difference between gas concentration and air flow rate. CO2 is measured with an infrared gas analyser (IRGA). ...
varioMAX CNS elemental analyser	The vario MAX CNS Elemental Analyser is a fully automatic instrument for the rapid and quantitative analysis of CNS and CN elements, capable of simultaneous determination of CNS or CN elements from a given sample in two modes/measurement modes. The vario MAX CNS analyser is only suitable for the analysis of samples with controllable combustibility depending on the mode or sample volume. The vario MAX CNS elemental analyser works on the principle of high temperature catalytic combustion with the introduction of oxygen. The gases produced as combustion products are purified from interfering foreign gases (e.g. volatile halogens). The required measurement components are separated by means of specific adsorption columns and then determined by a thermal conductivity detector (WLD). Helium (He) is used as a purge and carrier gas.	Responsible: Demeter Ibolya Organizational unit: University of Debrecen; Institutes for Agricultural Research and Educational Farm; Research Institute of Nyíregyháza; Basic and Applied Research Unit of Nyíregyháza; Department of Soil Biology and Soil Utilization E-mail: ibolyad85@gmail.com Phone: +06 (42) 594-300/320	- Analytical methods: elemental analysis of N, CN, CNS elements from sample Catalytic combustion of samples, separation of foreign gases, separation of the desired measurement components, WLD detection - Measurement of sample quantities: o 5 mg - 5 g (1 g organic matter, up to 5 ml, up to 200 or 400 mg C) - Measurement ranges: o CNS: 0,02-30 mg N abs. 0,02-200 mg C abs. 0,02-15 mg S abs.; o CN standard: 0,02-150 mg N abs. 0.02-200 mg C abs; o CN optional:
gas chromatograph	Currently not working	Responsible: Dr. Bak István Organizational unit: University of Debrecen; Faculty of Pharmacy; Department of Pharmacodynamics E-mail: bak.istvan@pharm.unideb.hu Phone: +06 (52) 255-586/55349	gas sampling loop, spl/spl less, capillary column, detectors: FID, TCD
gas chromatograph-mass spectrometer	GC-MS instrument with linear quadrupole analyser, split/splitless injection, direct sample introduction into MS, EI and CI ion source	Responsible: Dr. Bak István Organizational unit: University of Debrecen; Faculty of Pharmacy; Department of Pharmacodynamics E-mail: bak.istvan@pharm.unideb.hu Phone: +06 (52) 255-586/55349	Injectors: spl/spl less, capillary column, detectors: MSD
Liquid chromatograph-mass spectrometer	triplet quadrupole mass spectrometer with atmospheric pressure ion source	Responsible: Dr. Bak István Organizational unit: University of Debrecen; Faculty of Pharmacy; Department of Pharmacodynamics E-mail: bak.istvan@pharm.unideb.hu Phone: +06 (52) 255-586/55349	triplet quadrupole mass spectrometer, ESI-APCI ionisation, FIA, syringe pump or HPLC sample introduction
Ultrasound system for small animals	Using a pet ultrasound system, it is possible to monitor the rat heart "in vivo".	Responsible: Dr. Bak István Organizational unit: University of Debrecen; Faculty of Pharmacy; Department of Pharmacodynamics E-mail: bak.istvan@pharm.unideb.hu Phone: +06 (52) 255-586/55349	pet ultrasound system for rodents
High-shear granulator QUICKMIX25	The instrument is equipped with a 25 litre tank with a bottom mixer at the bottom and a chopper at the side, with adjustable speed. The tank jacket can be heated or cooled by water cooling. The granulation solution can be dispensed by pouring or pumping through the dispensing openings in the lid of the tank. The equipment is suitable for mixing dry powders and for wetting and granulation of powders in wet granulation. The product can be removed from the tank by means of a thickening valve.	Responsible: Dr. Fenyvesi Ferenc Organizational unit: University of Debrecen; Faculty of Pharmacy; Department of Pharmaceutical Technology E-mail: fenyvesi.ferenc@pharm.unideb.hu Phone: +36 (52) 411-717/54505	Mixing tank capacity: 25 L, Heated mantle up to 80 ˚C, Bottom mixer speed range 10-120 rpm, shredder speed adjustable in two speeds: 1440-2880 rpm.
Microencapsulator Büchi Encapsulator B-395 Pro	Encapsulator B-395 Pro can be used to produce capsules in sizes from 0.15-2 mm, typically using alginate or other suitable polymers. The material to be encapsulated should be mixed with the encapsulating polymer and loaded into the dispensing syringe. The apparatus is most suitable for encapsulation of particles below 50 µm. The apparatus is a semi-automatic device for the encapsulation of biomolecules, pharmaceutical active substances, flavours, fragrances, pigments, cells and micro-organisms under sterile and non-sterile conditions. The bead formation is based on a controlled laminar flow beam that is separated into beads of equal size by vibration at an optimum frequency.	Responsible: Dr. Fenyvesi Ferenc Organizational unit: University of Debrecen; Faculty of Pharmacy; Department of Pharmaceutical Technology E-mail: fenyvesi.ferenc@pharm.unideb.hu Phone: +36 (52) 411-717/54505	Droplet size: 0,15-2 mm, nozzle diameter (core) 0,08, 0,12, 0,15, 0,20, 0,30, 0,45, 0,75, 1,00 mm; shell nozzle diameter: 0,20, 0,30, 0,40, 0,50, 0,60, 0,70, 0,90 mm. Syringe pump output: 0,01-50 ml/min, Pump output with air pressure: 0,5-200 ml/min. Reactor gross volume: 4,5 litres, Reactor operating volume: 2 litres. Batch size: with syringe 2-60 ml, with overpressure pumping 5-1000 ml. Polymer mixture delivery: 70 ml/h-2500 ml/h depending on pumping and nozzle size.
Tablet presser RIVA PICCOLA MODELL B	The instrument is a tableting machine suitable for lab-scale or small/medium-scale tablet production.	Responsible: Dr. Fenyvesi Ferenc Organizational unit: University of Debrecen; Faculty of Pharmacy; Department of Pharmaceutical Technology E-mail: fenyvesi.ferenc@pharm.unideb.hu Phone: +36 (52) 411-717/54505	Tool type: B, Number of tools (stamps and dies): 10, Max. tablet diameter: 16 mm, Max. pressing force: 60 kN, Productivity: 3000-30000 tablets/hour,
GPC-RI	Gel permeation chromatography is a method for the analysis of polymer systems. The average and molecular weights of polymers can be determined with this instrument. Both synthetic and biopolymers can be analysed. The instrument is equipped with an RI (refractive index) detector, which provides universal detection capability.	Responsible: Nagy Tibor Organizational unit: University of Debrecen; Faculty of Pharmacy E-mail: nagy.tibor@science.unideb.hu Phone: +36 (52) 512-900/22452	The typical flow rate range of the Waters e2695 Separator is 0.050-5.000 mL/min, which can be varied in steps of 0.001 mL/min. The unit contains a degassing unit. The maximum pressure that can be applied to the system is 345 bar. The apparatus can hold 120 samples and the sample compartment is thermostable between 4 and 40 °C. The volume to be injected is variable from 0.1 to 100 µL. The system is controlled by EmpowerTM software. Measurements require a column system, determined by the type of s
Fluidized bed system Mini-Glatt	The instrument is a laboratory-scale fluidisation unit suitable for granulation and Wurster coating. The equipment is equipped with a Micro kit for small quantities of material. The fluid is fed into the unit by means of a peristaltic pump with adjustable speed.	Responsible: Dr. Fenyvesi Ferenc Organizational unit: University of Debrecen; Faculty of Pharmacy; Department of Pharmaceutical Technology E-mail: fenyvesi.ferenc@pharm.unideb.hu Phone: +36 (52) 411-717/54505	Product container volume: 0,75 L, Capacity: 50-350 g, Operating pressure 6 bar, Micro kit container volume: 5-100 ml, Micro kit capacity: 2,5-50 g, Spray nozzle: 0,5 and 0,8 mm, Wurster container volume: 150-600 ml, Inlet air heating up to max. 80 ˚C, Liquid dispensing pump max. flow rate 54 ml/min.
BX53 upright microscope	The instrument allows imaging of native, histochemically (colour reaction) and fluorescently labelled cells and tissues (sections) in transmitted light, polarisation mode and also in 3 fluorescence channels, in intelligent semi-automatic multi-area mode. The system also allows fluorescence calcium imaging at a maximum speed of 10 fps.	Responsible: Dr. Hegyi Zoltán Organizational unit: University of Debrecen; Faculty of Medicine; Department of Anatomy, Histology and Embryology E-mail: hegyiz@anat.med.unideb.hu Phone: +36 (52) 255-567/55441	BX-53 upright microscope, LED light source in 3 channels (DAPI, FITC and TRITC channels), polarizer and analyser,
Laser scanning confocal microscope	The instrument enables high-resolution imaging of fluorescently labelled cells and tissues (sections) in 4 fluorescence regions, with confocal optical slices in both time-lapse and multi-area modes.	Responsible: Dr. Hegyi Zoltán Organizational unit: University of Debrecen; Faculty of Medicine; Department of Anatomy, Histology and Embryology E-mail: hegyiz@anat.med.unideb.hu Phone: +36 (52) 255-567/55441	4 solid-state laser excitation sources (UV, 488,555, 647,; 2 PMT and 2 GAsP detectors, simultaneous detection of 4 channels; galvanometer scanner; super-resolution module (theoretical resolution 120 nm)
Two-photon microscope (equipped with titan-saphire laser system)	Femto 2D two-photon microscope 3D , with electrophysiology, optogenetics and resonance scanner upgrade. The system allows simultaneous microscopic imaging of in vitro electrophysiological measurements. List of measurement options (min. 5, max. 10): fluorescence microscopy, SHG microscopy, electrophysiology, Ca imaging, optogenetics, deep tissue imaging, time-lapse imaging	Responsible: Dr. Mészár Zoltán Mihály Organizational unit: University of Debrecen; Faculty of Medicine; Department of Anatomy, Histology and Embryology E-mail: meszarz@anat.med.unideb.hu Phone: +36 (52) 255-567/55490	Laser excitation source: 2-channel pulsed laser: 1) MaiTai 690-1040nm tunable, 100 fs, 2) HighQ2 1045 nm fixed, 250 fs fixed wavelength CW laser for optogenetic package. Detection: 3 simultaneous channel GAsP detectors, resonant and galvanometer scanner, line scan mode capability, optogenetics package, electrophysiology package.
TITAN-ZAFIR LESER (Two-photon microscope__equipped with titan-saphire laser)	Femto 2D two-photon microscope 3D , with electrophysiology, optogenetics and resonance scanner upgrade. The system allows simultaneous microscopic imaging of in vitro electrophysiological measurements. List of measurement options (min. 5, max. 10): fluorescence microscopy, SHG microscopy, electrophysiology, Ca imaging, optogenetics, deep tissue imaging, time-lapse imaging	Responsible: Dr. Mészár Zoltán Mihály Organizational unit: University of Debrecen; Faculty of Medicine; Department of Anatomy, Histology and Embryology E-mail: meszarz@anat.med.unideb.hu Phone: +36 (52) 255-567/55490	Laser excitation source: 2-channel pulsed laser: 1) MaiTai 690-1040nm tunable, 100 fs, 2) HighQ2 1045 nm fixed, 250 fs fixed wavelength CW laser for optogenetic package. Detection: 3 simultaneous channel GAsP detectors, resonant and galvanometer scanner, line scan mode capability, optogenetics package, electrophysiology package.
DSD2 (differential spinning disk)	The instrument allows imaging of fluorescently labelled cells and tissues (sections) in 4 fluorescence channels, producing confocal optical slices in both time-lapse and multi-area modes. Max. 30 fps for fluorescence calcium imaging.	Responsible: Dr. Hegyi Zoltán Organizational unit: University of Debrecen; Faculty of Medicine; Department of Anatomy, Histology and Embryology E-mail: hegyiz@anat.med.unideb.hu Phone: +36 (52) 255-567/55441	IX-83 motorized inverted microscope, metal halide excitation source, spinning disk module with 4 excitation side and 4 detector side filter pairs (DAPI, FITC, TRITC, Cy5); Andor Zyla 5.5 CMOS 3-tap camera, motorized stage
ATUMtome. Ultramicrotome with section collecting tape	Preparation of serial sections for transmission scanning electron microscopy	Responsible: Kis Nikoletta Gréta Organizational unit: University of Debrecen; Faculty of Medicine; Department of Anatomy, Histology and Embryology E-mail: greta@anat.med.unideb.hu Phone: +36 (52) 411-717/54402	-
High Pressure Freezer	Fast, efficient, automatic freezing of biological samples at high pressure	Responsible: Kis Nikoletta Gréta Organizational unit: University of Debrecen; Faculty of Medicine; Department of Anatomy, Histology and Embryology E-mail: greta@anat.med.unideb.hu Phone: +36 (52) 411-717/54402	-
Freeze Fracture System	The Leica EM BAF060 is a high-end sample preparation system for freeze fracturing, etching, and freeze drying of double replica, high resolution carbon/metal mix coatings for TEM and SEM analysis.	Responsible: Kis Nikoletta Gréta Organizational unit: University of Debrecen; Faculty of Medicine; Department of Anatomy, Histology and Embryology E-mail: greta@anat.med.unideb.hu Phone: +36 (52) 411-717/54402	The Leica EM BAF060 features an advanced microtome, flexible shadowing options with two independent electron beam sources and a load-lock transfer system.
Leica EM UC6 ultramicrotome	https://www.leica-microsystems.com/products/sample-preparation-for-electron-microscopy/p/leica-em-uc6/	Responsible: Dr. Kisvárday Zoltán Organizational unit: University of Debrecen; Faculty of Medicine; Department of Anatomy, Histology and Embryology E-mail: kisvarday@unideb.hu Phone: +36 (52) 255-724 Other contact: kisvarday@anat.med.unideb.hu,	Ultramicrotome for electron microscopy sections.
Opera Phenix High Content Screening System HH14000000	The Opera Phenix system is the most technologically advanced automated confocal cell analysis imaging system available. It is a high-throughput system suitable for phenotype-based screening as well as complex disease models using live cells, primary cells or microtissues. The Opera Phenix HCS system is designed for highly sensitive confocal imaging and high throughput with minimal optical crosstalk. The instrument employs a patent-protected Synchrony optical design that uniquely combines micro-lensed Nipkow rotating disk technology with dual-channel confocal optics to separate fluorescence excitation and emission during simultaneous imaging while minimizing spectral bleed-through to achieve higher speed and sensitivity. Four high-resolution sCMOS cameras provide unique parallel imaging for all four colours separately. Harmony® High Con	Responsible: Dr. Kókai Endre Organizational unit: University of Debrecen; Faculty of Dentistry; Division of Dental Biochemistry E-mail: ekokai@med.unideb.hu Phone: +36 (52) 412-345/61179 Other contact: Márton Zsolt zsolt.marton@med.unideb.hu 61182	The Opera Phenix "High Content Screening System" is a complex microscope (four cameras) with four different laser excitations (405, 488, 561, 640 nm), confocal mode and high throughput.
IVIS SpectrumCT In Vivo Imaging System	The integrated optics and micro CT technology of the instrument allows 3D reconstruction of bioluminescence and multispectral fluorescence signals in addition to their detection. In addition, the instrument is capable of autonomous subclassification of different techniques: - Low dose and ultra fast microCT imaging - 2D bioluminescence imaging - 2D multispectral fluorescence imaging - 2D Cerenkov imaging - DyCE™ dynamic enhanced imaging for real-time studies	Responsible: Mocsár Gábor Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biophysics and Cell Biology E-mail: mocsgab@med.unideb.hu	The IVIS SpectrumCT In Vivo Imaging System is a 3D multimodular small animal imaging system capable of detecting fluorescence and bioluminescence signals and their 3-dimensional reconstruction.
Yobin Yvon Fluorolog spectrofluorometer	Dual-path excitation and emission monochromators, cooled photon counter PMT, L and T format, UV to IR Xe lamp, fluorescence excitation and emission spectra, fluorescence anisotropy, time-dependent measurement, FRET, thermostatted 4-cuvette sample holder.	Responsible: Mocsár Gábor Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biophysics and Cell Biology E-mail: mocsgab@med.unideb.hu	Yobin Yvon Fluorolog fluorescence spectrofluorimeter
Electrophysiology workstation – Nikon eclipse microscope	The instrument consists of an electrophysiological measuring station, an inverted fluorescence microscope on a vibration-free table, data acquisition devices and a personal computer connected to the instrument. The measuring station is combined with a multi-channel fluorescence camera, which allows the investigation of intracellular Ca2+ concentrations in single cells using Ca2+ sensitive fluorescent dyes (e.g. Fura2, time-dependent ratiometric measurements) and the simultaneous characterisation of Ca2+ concentration changes and electrophysiological parameters.	Responsible: Mocsár Gábor Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biophysics and Cell Biology E-mail: mocsgab@med.unideb.hu	Nikon eclipse fluorescence microscope, amplifier, perfusion system, thermostat.
Electrophysiology workstation – DeltaScan microscope fluorimeter	The instrument consists of an electrophysiological measuring station, an inverted fluorescence microscope on a vibration-free table, data acquisition devices and a personal computer connected to the instrument. The measuring station is combined with a PTI DeltaScan multichannel fluorescence microscope, which provides the possibility to study intracellular Ca2+ concentrations in single cells using Ca2+ sensitive fluorescent dyes (e.g. Fura2, time-dependent ratiometric measurements) and to characterise Ca2+ concentration changes and electrophysiological parameters simultaneously.	Responsible: Mocsár Gábor Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biophysics and Cell Biology E-mail: mocsgab@med.unideb.hu	Nikon TE-2000 fluorescence microscope, amplifier, AD/DA converter, perfusion system micromanipulator, PTI-DeltaScan microscopic fluorimeter
Nikon N-STORM Super-Resolution Inverted Microscope	The super-resolution microscope is a four-laser excitation super-resolution (STORM) and confocal mode microscope. The wavelengths and powers of the laser lines are 405 nm (20 mW), 488 nm (20 mW), 561 nm (70 mW) and 647 nm (120 mW). The microscope slide stage has software-based automatic focus stabilisation and light reflection-based (hardware) focus stabilisation. The microscope is equipped with a STORM quadband 405/488/561/647 motorized filter frame, an apochromatic TIRF 100x oil immersion objective and a 60x apochromatic water immersion objective for confocal mode. The microscope is capable of single molecule detection in fixed and live cell samples using dSTORM, 3D STORM, TIRF techniques with high resolution CCD camera.	Responsible: Mocsár Gábor Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biophysics and Cell Biology E-mail: mocsgab@med.unideb.hu	The Nikon Ti-E inverted super-resolution microscope (~20 nm) is a microscope with four laser excitations (405, 488, 561 and 647 nm) in superfold (2D and 3D STORM) and confocal modes.
OLYMPUS FluoView FV1000 confocal microscope	Equipment for microscopic tomography (optical slicing) and detection of molecular mobility and co-movement. The microscope's 3 lasers provide excitation wavelengths of 456, 470, 488, 514, 543 and 633 nm. 3 fluorescence signals, 2 of which are spectrally resolved, and a transmitted light signal (DIC contrast) can be detected simultaneously. By scanning, images with an optical slice thickness of 0.5 μm can be obtained, from which the 3D image of the sample, the spatial distribution of biomolecules and their colocalisation can be reconstructed. The microscope is equipped with a custom-designed three-channel fluorescence correlation and cross-correlation spectroscope (FCS, FCCS) for FCS measurements in a selected (0.3 μm3) volume fraction of the cell.	Responsible: Mocsár Gábor Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biophysics and Cell Biology E-mail: mocsgab@med.unideb.hu	Olympus FluoView 1000 confocal laser scanning microscope and fluorescence correlation spectroscope. 456, 470, 488, 514, 543 and 633 nm illumination, 3 fluorescence and correlation detectors.
Olympus - TIRF total internal reflection fluorescence microscope	Total Internal Reflection Fluorescence Microscopy is a method for the sensitive and sensitive examination of cell membranes, near-membrane cell organelles and samples on coverslips. Excitation light from the objective with high NA is incident at an angle greater than the critical angle at the glass-water (cover-slab) interface, where it is fully reflected. However, the exponentially decaying so-called evanescent field at the reflection site can excite the dyes in the layer close to the sample interface (down to ~100-200 nm), but does not reach the inner layers of the sample. Thus, for example, a specific fluorescence signal can be obtained from the cell membrane at very low background. The sensitivity of the method is significantly higher than that of confocal microscopy for surface applications (ligand binding, internalization, membrane proteins and lipids, etc.).	Responsible: Mocsár Gábor Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biophysics and Cell Biology E-mail: mocsgab@med.unideb.hu	The microscope is equipped with 4 lasers (405, 491, 561, 647 nm). The Andor iXon 897 EMCCD camera can capture images every 20 ms. The microscope is equipped with an optical splitter which allows simultaneous acquisition of spectrally separated (e.g. green and red) images on both sides of the CCD chip of the camera. The inspection layer thickness (the penetration depth of the evanescent field) can be automatically adjusted by varying the angle of incidence for each laser line.
Zeiss LSM880 – Airy-scan confocal laser scanning microscope	Equipment for microscopic tomography (optical slicing) and detection of molecular mobility and co-movement. By scanning, images with an optical slice thickness of 0.5 μm can be obtained, from which the 3D image of the sample, the spatial distribution of biomolecules and their colocalisation can be reconstructed. The microscope is equipped with a fluorescence correlation and cross-correlation spectroscopy unit (FCS, FCCS), which allows FCS measurements in a selected volume fraction of the cell (0.3 μm3).	Responsible: Mocsár Gábor Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biophysics and Cell Biology E-mail: mocsgab@med.unideb.hu	ZEISS LSM 880 AiryScan. laser illumination: 405, 458, 488, 515, 561 and 633 nm; confocal and AiryScan scanning unit.
FLIM-TIRF Fluorescence Lifetime Imaging Microscope	Fluorescence lifetimes can be determined by phase and depth of modulation in live or fixed cells or other samples. Changes in fluorescence lifetime can be used to infer FRET efficiency, changes in the molecular environment of fluorophores, and changes in molecular interactions. Full internal reflection illumination allows specific, highly sensitive analysis of cell membrane, near-membrane cell organelles, cover slip samples. Autofocus, focus stabilization and 3D repositioning with motorized stage.	Responsible: Mocsár Gábor Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biophysics and Cell Biology E-mail: mocsgab@med.unideb.hu	Lambert Instruments fluorescence lifetime measuring unit mounted on an inverted Olympus IX81 fluorescence microscope. Illumination: 4 modulated LEDs (405-640 nm range) modulated lasers (445, 488 and 633 nm). Detection: fast CCD camera with MCP amplifier. The lasers are suitable for TIRF illumination, additional lasers can be integrated in the green-yellow range.
LSC – iCys laser scanning cytometer	The device is a microscope-based instrument that combines the advantages of the flow cytometer and the microscope and fills the methodological gap between them. It resolves the fundamental "which few cells to examine among many different ones" problem of biological variability associated with digital image analysis microscopy as a technique for dealing with individual cells, and it is capable of population-level imaging of scattering cells attached to a slide that is impractical with flow cytometry. Measurement per cell includes cell location, measurement time, cell area, cell circumference, total cell fluorescence intensity, peak fluorescence intensity within the cell, fluorescence intensity scatter, similar chromatic intensity, peak intensity and scatter signals, and additional derived calculated image parameters. The software allows to remove the slide after examination of the sample, to perform e.g. staining on the cells of the sample, and then to	Responsible: Mocsár Gábor Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biophysics and Cell Biology E-mail: mocsgab@med.unideb.hu	The cytometer is equipped with three lasers (405, 488 and 633 nm), five data acquisition channels per laser and eight interchangeable filter blocks. The instrument is built on an Olympus IX71 inverted fluorescence microscope, equipped with an electronically controlled slide stage, 10X, 25X, 40X and 60X objectives, a high-resolution digital camera and dedicated control software.
Novocyte 3000 RYB flow cytometer	The instrument can measure the light scattering and different fluorescence characteristics of a large number of cells in a short time, accurately and reproducibly. The instrument is suitable for conventional fluorescence intensity measurements, but also for the determination of more complex biophysical parameters such as fluorescence resonance energy transfer (FRET). Using the intensity data of fluorescent dyes per cell, information on the following cell characteristics and their distribution within the cell population can be obtained: intracellular and cell surface protein expression levels (fluorescent dye-conjugated antibody labeling); cell viability (calcein-AM, FDA and/or propidium iodide); intracellular pH (BCECF-AM); membrane potency (oxonol); DNA content, which can be used to characterise cells at different stages of the cell cycle; and intracellular accumulation of fluorescent substrates of ABC transporters (e.g. daunorubicin, doxorubicin, calcein, rhodamine 123).	Responsible: Mocsár Gábor Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biophysics and Cell Biology E-mail: mocsgab@med.unideb.hu	The instrument is equipped with three lasers (488 nm, 561 nm, 640 nm) and a total of 7 photoelectron multiplier detectors capable of detecting fluorescence. In addition, the instrument is equipped with forward scatter and side scatter detectors. It requires minimal adjustment by the user.
Zeiss LSM 510 confocal microscope, correlation spectroscope	Zeiss LSM510 - Confocor 2 confocal laser scanning microscope and fluorescence correlation spectroscope. Its user-friendly interface and its complete set-up make it suitable for microscopic examinations requiring simple axial resolution up to more complex quantitative analyses (FRET, FRAP, FLIP, spatial correlations). The instrument is unique in its dual-channel fluctuation detector and real-time correlator (Confocor 2), which can measure temporal cross-correlation, and is able to characterise the concentration, diffusion constants and co-diffusion of fluorescently labelled molecules in suspension and in defined subcellular spaces of cells, and from these the mobility and interactions of molecules.	Responsible: Mocsár Gábor Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biophysics and Cell Biology E-mail: mocsgab@med.unideb.hu	The instrument consists of two parts, a common laser module and a fully motorized inverted microscope body mounted on an epifluorescence stage. One scanning stage allows conventional laser confocal microscopy with laser excitation at 351, 364, 458, 477, 488, 514 543 and 633 nm, 3 photoelectron multipliers and a spectral diode array detector, the latter with 8 different emission channels defined in addition to spectral use, and a transmission detector
BD FACS Calibur flow cytometer	Available lasers: 488nm, 632nm, Multicolor flow cytometric analysis: 4 fluorescence parameters can be simultaneously detected.	Responsible: Botó Pál Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biochemistry and Molecular Biology E-mail: paul.boto@gmail.com Phone: +06 (52) 512-900/64593	Available lasers: 488nm, 632nm, Multicolor flow cytometric analysis: 4 fluorescence parameters can be simultaneously detected.
LC 480	The LC 480 is a real-time quantitative PCR instrument using a 384-well PCR plate. The instrument can be used to perform hydrolysis assays and Sybr green based measurements.	Responsible: Dr. Póliska Szilárd Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biochemistry and Molecular Biology E-mail: poliska@med.unideb.hu Phone: +06 (52) 411-717/50216	-
Illumina HiScanSQ	-	Responsible: Dr. Póliska Szilárd Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biochemistry and Molecular Biology E-mail: poliska@med.unideb.hu Phone: +06 (52) 411-717/50216	-
GETINGE AUTOKLAV	Sterilises packaged or unwrapped utensils, bedding, feed at 121°C to 134°C using high pressure steam.	Responsible: Kurucz Viktória Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biochemistry and Molecular Biology E-mail: kurucz.viktoria@med.unideb.hu Phone: +36 (52) 411-600/62325	steam sterilizer
Oxymax-CLAMS	The device allows the simultaneous measurement of calorimetric and metabolic parameters of 8 mice. The parameters measured are O2 consumption, CO2 production, RER (calculated), Heat production (calculated), food consumption, water consumption volume and frequency, locomotor activity along the X axis, sleep period (calculated from activity).	Responsible: Pap Attila Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biochemistry and Molecular Biology E-mail: papa@med.unideb.hu Phone: +36 (52) 411-600/65234	The instrument allows the simultaneous measurement of calorimetric and metabolic parameters of 8 mice. The instrument consists of 8 hermetically sealed chambers and associated supply and detection units, a computer and a monitor where the measured data are recorded and analysed using the installed software. When the values are exported, the files can be converted to Excel, allowing further analysis independently of the computer. Translated with DeepL.com (free version)
HPLC system	The Watres HPLC system is suitable for the separation of different analytes. The instrument is equipped with four HPLC pumps, which allows the use of four different solvents. The PDA detector of the instrument allows the analysis of analytes over a wide wavelength range and also provides the possibility of quantitative determination of the analytes.	Responsible: Dr. Csösz Éva Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biochemistry and Molecular Biology E-mail: cseva@med.unideb.hu Phone: +36 (52) 512-900/55734	Applicable solvents: max. 4; Flow rate: 0.010-10 ml/min; Pressure: max. 5000 psi; Injection volume: 0.1-100µl; Heated column thermostat.
Transcend II on-line sample preparation system	Sample preparation is performed on a TurboFlow column under turbulent flow conditions, using a combined separation involving both size exclusion and chemical sequestration. The internal surface of the column is covered with a bound stationary phase, the polarity of which can be selected from the apolar to the polar surface according to the analytical task. The column effectively separates the high molecular weight matrix from the low molecular weight target compound. The system can be operated as a conventional UPLC and allows separation of small and large molecules using TurboFlow. It is particularly suitable for the analysis of small molecules from complex matrices without a prior sample preparation step.	Responsible: Dr. Csösz Éva Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biochemistry and Molecular Biology E-mail: cseva@med.unideb.hu Phone: +36 (52) 512-900/55734	Column particle size: >30 µm; flow rate: 0.5-5 ml/min; cross-contamination rate: <30ppm
Centrikon T-1180 ultracentrifuge	The instrument is suitable for preparative centrifugation of various complex samples. The instrument is compatible with both fixed and swing arm rotors. In addition to simple preparative centrifugation, it is also suitable for gradient centrifugation, isolation of micro-soma fractions, and purification of viruses and bacteriophages.	Responsible: Dr. Csösz Éva Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biochemistry and Molecular Biology E-mail: cseva@med.unideb.hu Phone: +36 (52) 512-900/55734	Coolable rotor chamber, adjustable acceleration and braking. Rotor types. Type 35: max 35000 rpm; TFT 50.38Ti: max. 50000 rpm; Type 50: max. 40000 rpm; SW41 Ti: max. 41000 rpm; SW 55 Ti: max 55000 rpm; Type 19: max. 19000 rpm; TZT 42-650: max. 42000 rpm.
Nano LC-MS/MS system	To reduce the complexity of the biological samples, the system is equipped with a nanoHPLC instrument to ensure proper separation of complex biological samples. The mass spectrometer has a tandem design with three quadrupole analysers, the third of which can be operated as a linear ion trap. The instrument offers the possibility of both single and tandem mass spectrometry measurements. In Information Dependent Acquisition (IDA) mode, it is possible to determine the composition of unknown samples. In addition, the instrument can perform analyses in precursor ion scan, fragment ion scan and neutral loss scan modes. In Multiple Reaction Monitoring/Selected Reaction Monitoring (MRM/SRM) mode, targeted quantitative analyses can be performed.	Responsible: Dr. Csösz Éva Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biochemistry and Molecular Biology E-mail: cseva@med.unideb.hu Phone: +36 (52) 512-900/55734	EASY nLC II :Flow rate: in the range of 20-2000 nl/min (100-1000 nl/min recommended); Maximum pressure: 300 bar; Injection volume: 1-18 µl 4000 QTRAP: Bulk range: Q1/Q3/RF/DC mode 5-2800 m/z, linear ion trap mode 50-2800 m/z; Resolution: 609 m/z at 250 amu/sec scan rate >3000; Dynamic range: 1-4x106 cps; Velocity: 250 amu/sec, 1000 amu/sec and 4000 amu/sec scan rate in linear ion trap mode, up to 2400 amu/sec in RF/DC mode.
nanoUPLC-Orbitrap Fusion Tribrid mass spectrometer	To reduce the complexity of the biological samples, the system is equipped with a nanoUPLC device to ensure proper separation of complex biological samples. The mass spectrometer is a tandem design, consisting of three different analysers, a quadrupole, an orbitrap and an ion trap analyser. Due to the operation of the analysers, different measurement modes and different fragmentation patterns can be obtained with the instrument.	Responsible: Dr. Csösz Éva Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biochemistry and Molecular Biology E-mail: cseva@med.unideb.hu Phone: +36 (52) 512-900/55734	Bulk range: 50-6000 m/z; Resolution: 15000-450000 for 200 m/z; Scanning rate: 20 Hz; Bulk accuracy: <1ppm for internal calibration, <3 ppm for external calibration; MS/MS sensitivity: 100fg reserpine; Dynamic range: >5000.
ULTRA HIGH PRESSURE NANO HPLC DEVICE	To reduce the complexity of the biological samples, the system is equipped with a nanoUPLC device to ensure proper separation of complex biological samples. The mass spectrometer is a tandem design, consisting of three different analysers, a quadrupole, an orbitrap and an ion trap analyser. Due to the operation of the analysers, different measurement modes and different fragmentation patterns can be obtained with the instrument	Responsible: Dr. Csösz Éva Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biochemistry and Molecular Biology E-mail: cseva@med.unideb.hu Phone: +36 (52) 512-900/55734	Bulk range: 50-6000 m/z; Resolution: 15000-450000 for 200 m/z; Scanning rate: 20 Hz; Bulk accuracy: <1ppm for internal calibration, <3 ppm for external calibration; MS/MS sensitivity: 100fg reserpine; Dynamic range: >5000.
Acquity H-class UPLC system	The Acquity H-class UPLC system is suitable for the fast and efficient separation of different analytes. The instrument is equipped with four UPLC pumps, which allows the use of four different solvents. The combination of the four solvents allows the creation of complex separation profiles for the most precise separation of individual analytes. The instrument's PDA detector allows the determination of analytes over a wide wavelength range and also provides the possibility to quantify the analytes.	Responsible: Dr. Csösz Éva Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biochemistry and Molecular Biology E-mail: cseva@med.unideb.hu Phone: +36 (52) 512-900/55734	Flow rate: range 0.010 ml/min-2.2 ml/min; Maximum pressure: 15,000 psi at 1ml/min, 7800 psi at 2.2ml/min; pH range: 2-12; Maximum four solvents; Injection volume: 0.1-10 µl; Adjustable column thermostat with temperature range 20-90 oC; PDA detector.
Two dimensional electrophoresis system	Using the two-dimensional electrophoresis system, it is possible to analyse the complete proteome of complex biological samples. The first step of separation is isoelectric focusing, where proteins are separated by their isoelectric point. Separation can be performed on strips of different sizes. The second dimension is polyacrylamide gel electrophoresis, where proteins separated by isoelectric focusing are also separated by size. Visualization of protein spots can be done with different stains. Gel documentation is performed by the Pharos FX-Plus scanner. Depending on the laser setting, several types of colorimetric, fluorescence and isotope-based detection are possible. After software analysis of the gel images, both qualitative and quantitative differences between samples can be detected. Various post-translational modifications can also be investigated using special dyes.	Responsible: Dr. Csösz Éva Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biochemistry and Molecular Biology E-mail: cseva@med.unideb.hu Phone: +36 (52) 512-900/55734	Isoelectric focusing device: 50-1000V, 0-2.4mA, 0-24W; Strip size: 7cm, 17cm and 24cm. Electrophoresis cell: capable of running up to 12 polyacrylamide gels of up to 24cm within a maximum range of 1000V and 250W. Pharos FX-Plus scanner: Linear dynamic range: 1:65535; Resolution: 50, 100, 200 and 800 µm, Internal and external laser module, Fluorescence detection options: ethidium bromide, SYBR Green I, SYBR Gold, SYPRO Orange, SYPRO Red, Nile Red, SYPRO Ruby, Deep Purple, Alexa 448, Alexa
NANO HPLC /PROXEON/	To reduce the complexity of the biological samples, the system is equipped with a nanoHPLC instrument to ensure proper separation of complex biological samples. The mass spectrometer has a tandem design with three quadrupole analysers, the third of which can be operated as a linear ion trap. The instrument offers the possibility of both single and tandem mass spectrometry measurements. In Information Dependent Acquisition (IDA) mode, it is possible to determine the composition of unknown samples. In addition, the instrument can perform analyses in precursor ion scan, fragment ion scan and neutral loss scan modes. In Multiple Reaction Monitoring/Selected Reaction Monitoring (MRM/SRM) mode, targeted quantitative analyses can be performed.	Responsible: Dr. Csösz Éva Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biochemistry and Molecular Biology E-mail: cseva@med.unideb.hu Phone: +36 (52) 512-900/55734	EASY nLC II :Flow rate: in the range of 20-2000 nl/min (100-1000 nl/min recommended); Maximum pressure: 300 bar; Injection volume: 1-18 µl 4000 QTRAP: Bulk range: Q1/Q3/RF/DC mode 5-2800 m/z, linear ion trap mode 50-2800 m/z; Resolution: 609 m/z at 250 amu/sec scan rate >3000; Dynamic range: 1-4x106 cps; Velocity: 250 amu/sec, 1000 amu/sec and 4000 amu/sec scan rate in linear ion trap mode, up to 2400 amu/sec in RF/DC mode.
BD FACS ARA III flow cytometer and cell sorter	Available lasers: 375nm, 405nm, 445nm, 488nm, 561nm, 633nm. Multicolor flow cytometric analysis: 18 fluorescence parameters can be simultaneously detected. Capable of 2 and 4 way sorting, plate sorting, sorting onto slide.	Responsible: Botó Pál Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biochemistry and Molecular Biology E-mail: paul.boto@gmail.com Phone: +06 (52) 512-900/64593	Available lasers: 375nm, 405nm, 445nm, 488nm, 561nm, 633nm. Multicolor flow cytometric analysis: 18 fluorescence parameters can be simultaneously detected. Capable of 2 and 4 way sorting, plate sorting, sorting onto slide.
ABI Prism 3100-Avant Genetic Analyzer	The ABI Prism 3100-Avant Genetic Analyzer is a 4-capillary sequencer for sequencing based on the chain termination method (Sanger method) and is also suitable for fragment analysis.	Responsible: Dr. Póliska Szilárd Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biochemistry and Molecular Biology E-mail: poliska@med.unideb.hu Phone: +06 (52) 411-717/50216	4-capillary sequencer with 50 cm capillary length, calibrated for BigDye 3.1 and BigDye 1.1 sequencing chemistry and fragment analysis DS-30 filter D dye set calibration: 6FAM, HEX, NED, ROX and DS-33 filter G5 dye set calibration: 6-FAM™, VIC®, NED™, PET®, LIZ®.
Illumina NextSeq500	The Illumina NextSeq500 is suitable for so-called single read and paired-end sequencing runs, the length of the read is flexible and can be adapted to most new generation sequencing applications.	Responsible: Dr. Póliska Szilárd Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biochemistry and Molecular Biology E-mail: poliska@med.unideb.hu Phone: +06 (52) 411-717/50216	- Flow cel configuration :High-output flow cel (400 M single read, 800 M paired-end read) Read length: 1 x 75 bp, 2 x 75 bp, 2 x 150 bp Data volume (giga base pairs): 30, 60,120 Run time (hours): > 80% > Q30, > 80% > Q30, > 75% > Q30 - Flow cel configuration : Mid-output flow cel (130 M single read, 260 M paired-end read) Read length: 2 x 75 bp, 2 x 150 bp Data volume (giga base pairs): 19, 39, Run time (hours): > 80% > Q30, > 75% > Q30
Illumina NextSeq500	The Illumina NextSeq500 is suitable for so-called single read and paired-end sequencing runs, the length of the read is flexible and can be adapted to most new generation sequencing applications.	Responsible: Dr. Póliska Szilárd Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biochemistry and Molecular Biology E-mail: poliska@med.unideb.hu Phone: +06 (52) 411-717/50216	- Flow cel configuration :High-output flow cel (400 M single read, 800 M paired-end read) Read length: 1 x 75 bp, 2 x 75 bp, 2 x 150 bp Data volume (giga base pairs): 30, 60,120 Run time (hours): > 80% > Q30, > 80% > Q30, > 75% > Q30 - Flow cel configuration : Mid-output flow cel (130 M single read, 260 M paired-end read) Read length: 2 x 75 bp, 2 x 150 bp Data volume (giga base pairs): 19, 39, Run time (hours): > 80% > Q30, > 75% > Q30
Affymetrix microarray system	The Affymetrix microarray system is suitable for gene expression and clinical genetic testing based on gene chip hybridization. The system can only handle Affymetrix arrays/gene chips. For gene expression experiments, gene chips specific for human, mouse, rat and other laboratory model organisms are available. These chips can be used to test the trnascriptome at the global level. For clinical genetic applications, cytogenetic and SNP6.0 human gene chips are available.	Responsible: Dr. Póliska Szilárd Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biochemistry and Molecular Biology E-mail: poliska@med.unideb.hu Phone: +06 (52) 411-717/50216	-
QuantStudio 12K flex	QuantStudio is a real-time quantitative PCR instrument that can accommodate 96-well and 384-well PCR plates. Two special blocks are available: 1) TaqMan microdfluidic card, 384 reactions can be performed on one card. 2) Openarray plate, 3072 reactions can be performed on one plate. For more information on the TaqMan microfluidic card and OpenArray plate options, please visit the Thermo Ficher Scientific website (https://www.thermofisher.com).	Responsible: Dr. Póliska Szilárd Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biochemistry and Molecular Biology E-mail: poliska@med.unideb.hu Phone: +06 (52) 411-717/50216	-
PCR BLOCK DEVICE HIGH PERMEABILITY	Openarray plate, 3072 reactions can be performed on one plate. For more information on the TaqMan microfluidic card and OpenArray plate options, please visit the Thermo Ficher Scientific website (https://www.thermofisher.com).	Responsible: Dr. Póliska Szilárd Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biochemistry and Molecular Biology E-mail: poliska@med.unideb.hu Phone: +06 (52) 411-717/50216	-
Optima AUC – Analytical Ultracentrifuge	OPTIMA AUC is the latest type of analytical ultracentrifuge. During analytical ultracentrifugation, the centrifugal force causes the biomolecules to sediment in the direction of the force. This sedimentation can be monitored in real time by the analytical ultracentrifuge using two types of optical systems: (I) an absorbance module (II) an interference module. The absorbance module is able to track biomolecules at predefined wavelengths, while the interference module detects differences between sample and reference cells at fixed wavelengths. The instrument is primarily designed to study the thermodynamic and hydrodynamic properties of proteins, but its wide wavelength range makes it suitable for the analysis of other biomolecules.	Responsible: Duró Norbert Ádám Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biochemistry and Molecular Biology E-mail: duro.norbert@med.unideb.hu Phone: +06 (30) 417-5855	- 50.000 rpm (~ 200.000 x g) - 4 - 40℃ temperature - interference module (660 nm) - absorbance module (180-800 nm) - < 5 µmHg
FlexStation II 384 Multimode microplate reader with integrated liquid handling module	Multimodality microplate reader with a variety of optical measurement options in 6-384 well-plate formats. During measurement, up to 3 pipetting options with integrated liquid handling module in 96 and 384 well formats, requiring own specific disposable pipette tips. Detection and extinction wavelength adjustment using independent monochromators	Responsible: Dr. Tóth István Balázs Organizational unit: University of Debrecen; Faculty of Medicine; Department of Physiology E-mail: toth.istvan@med.unideb.hu Phone: +36 (52) 411-717/54212	Excitation range: 250-850 nm, Emission range: 360-850 nm, monochromator; pipetting range: 2-100 ul, 8 or 16 channels
FLUORESCENT SPECTROFOTOMETER / PTI deltascan	fluorescence measuring system for fluorescent dye-filled cells	Responsible: Dr. Szentandrássy Norbert Organizational unit: University of Debrecen; Faculty of Dentistry; Institute for General Medical Knowledge E-mail: szentandrassy.norbert@med.unideb.hu	fluorescence measuring system
SPEKTROFOTOMÉTER /FLUORESCENS/ / PTI deltascan	fluorescence measuring system for fluorescent dye-filled cells	Responsible: Dr. Szentandrássy Norbert Organizational unit: University of Debrecen; Faculty of Dentistry; Institute for General Medical Knowledge E-mail: szentandrassy.norbert@med.unideb.hu	fluorescence measuring system
MULTICLAMP 700B- INTRACELLULÁRIS ERŐSÍTŐ ESZKÖZ	intracellular amplifier	Responsible: Dr. Horváth Balázs Organizational unit: University of Debrecen; Faculty of Pharmacy; Dean’s office, Faculty of Pharmacy E-mail: horvath.balazs@med.unideb.hu	intracellular amplifier
Microscope (fast laser scanning confocal)	Ultrafast laser scanning confocal microscope.	Responsible: Dr. Hermanné Dr. Dienes Beatrix Éva Organizational unit: University of Debrecen; Faculty of Medicine; Department of Physiology E-mail: dienes.beatrix@med.unideb.hu Phone: +36 (52) 255-575/55933	405 nm, 458/488/515 nm and 561 nm lasers; LIVE line scanning unit; inverting microscope; Patch Clamp measurement system.
Microscope (laser scanning confocal)	laser scanning confocal microscope. Combined with the META detector, it provides high spectral resolution, allowing up to 6-8 simultaneous fluorescence labels.	Responsible: Dr. Hermanné Dr. Dienes Beatrix Éva Organizational unit: University of Debrecen; Faculty of Medicine; Department of Physiology E-mail: dienes.beatrix@med.unideb.hu Phone: +36 (52) 255-575/55933	405 nm, 458/488/515 nm, 561 nm and 633 nm lasers; META scanning unit, up-right microscope.
Microscope	Platform egy kalcium képalkotó rendszerhez. A CollLed megvilágítási rendszer hamarosan telepítésre kerül.	Responsible: Dr. Hermanné Dr. Dienes Beatrix Éva Organizational unit: University of Debrecen; Faculty of Medicine; Department of Physiology E-mail: dienes.beatrix@med.unideb.hu Phone: +36 (52) 255-575/55933	Calcium imaging system based on. The ColLed illumination system will be installed soon.
Confocal Microscope	out of order	Responsible: Dr. Hermanné Dr. Dienes Beatrix Éva Organizational unit: University of Debrecen; Faculty of Medicine; Department of Physiology E-mail: dienes.beatrix@med.unideb.hu Phone: +36 (52) 255-575/55933	inoperable
Spectrophotometer	Spectrophotometer	Responsible: Dr. Almássy János Organizational unit: University of Debrecen; Faculty of Medicine; Department of Physiology E-mail: almassy.janos@med.unideb.hu Phone: +06 (30) 433-1450	Spectrophotometer
Confocal microscope with accessories	Laser scanning confocal microscope with Airy scan detector.	Responsible: Dr. Hermanné Dr. Dienes Beatrix Éva Organizational unit: University of Debrecen; Faculty of Medicine; Department of Physiology E-mail: dienes.beatrix@med.unideb.hu Phone: +36 (52) 255-575/55933	405 nm, 458/488/515 nm, 561 nm and 633 nm lasers; standard and AiryScan scanning unit; inverting microscope; Patch Clamp measuring system
SCANNING UNIT	Laser scanning confocal microscope with Airy scan detector.	Responsible: Dr. Hermanné Dr. Dienes Beatrix Éva Organizational unit: University of Debrecen; Faculty of Medicine; Department of Physiology E-mail: dienes.beatrix@med.unideb.hu Phone: +36 (52) 255-575/55933	405 nm, 458/488/515 nm, 561 nm and 633 nm lasers; standard and AiryScan scanning unit; inverting microscope; Patch Clamp measuring system.
SUPER SCANNING UNIT	Laser scanning confocal microscope with Airy scan detector.	Responsible: Dr. Hermanné Dr. Dienes Beatrix Éva Organizational unit: University of Debrecen; Faculty of Medicine; Department of Physiology E-mail: dienes.beatrix@med.unideb.hu Phone: +36 (52) 255-575/55933	405 nm, 458/488/515 nm, 561 nm and 633 nm lasers; standard and AiryScan scanning unit; inverting microscope; Patch Clamp measuring system.
ABI Prism 7000, Quantitative PCR equipment	Older type Q-PCR instrument	Responsible: Dr. Tóth István Balázs Organizational unit: University of Debrecen; Faculty of Medicine; Department of Physiology E-mail: toth.istvan@med.unideb.hu Phone: +36 (52) 411-717/54212	96 well block, 4 channel fluorescence detection with CCD camera, 4-95 oC,
AKTA purifier 10	https://manualzz.com/doc/6906688/%C3%A4ktapurifier-user-guide---ge-healthcare-life-sciences	Phone: +36 (30) 358-7385 Other contact: Szakácsi János, szakacsi@belklinika.com, +36 303587385	https://manualzz.com/doc/6906688/%C3%A4ktapurifier-user-guide---ge-healthcare-life-sciences
AB 7500 Real-Time PCR System	-	Responsible: Ujszászi Sándor Organizational unit: University of Debrecen; Faculty of Medicine; Department of Human Genetics E-mail: ujszaszi.sandor@med.unideb.hu Phone: +36 (30) 940-5736/65168 Other contact: ujsanyi@vipmail.hu	-
EnVision 2105 Multimode Plate Reader	The Envision multiplate reader is a dual-detector, dual-emission system that provides excellent capability for all non-radiometric reading technologies, including AlphaScreen®, AlphaLISA®, fluorescence, ultra-sensitive luminescence, absorbance, time-resolved fluorescence (TRF) and TR-FRET, allowing the determination of a wide range of intracellular processes and cellular phakors. The instrument is equipped with an automatic dispenser for 50 plate sequential measurements and a thermostable dual-channel liquid dispenser for measurements up to 55 °C.	Responsible: Dr. Szöllösi János Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biophysics and Cell Biology; Division of Biophysics E-mail: szollo@med.unideb.hu Phone: +36 (52) 411-717/65104	-
FACS Vantage DiVa digital sorter-flow cytometer	The instrument is modular and can be assembled to meet specific measurement needs. Separate laser heads (some of which require water cooling!) and multiple (max. 3) laser excitation wavelengths can be varied. The device is unfortunately not at all user friendly, use with operator assistance is recommended. The instrument has not been in use for a long time and can take days to set up if required. Currently, only fluorescence polarization studies and the possibility of UV excitation would justify its use.	Responsible: Dr. Gogolák Péter Organizational unit: University of Debrecen; Faculty of Medicine; Department of Immunology E-mail: gogy@med.unideb.hu Phone: +36 (52) 411-717/68888	First generation (~15 years old) digital "Jet in the air" sorter/flow cytometer, capable of measuring up to 9-10 parameters simultaneously. Variable architecture. Replaceable light filters and ballast mirrors, polarizing filters
ACEA NovoCyte 2000R Flow Cytometer	User friendly, compact benchtop flow cytometer with blue and red laser excitation for use with conventional FITC, PE, PerCP, and APC fluorescent dyes. It is also possible to determine sample volume and thus absolute cell count.	Responsible: Dr. Gogolák Péter Organizational unit: University of Debrecen; Faculty of Medicine; Department of Immunology E-mail: gogy@med.unideb.hu Phone: +36 (52) 411-717/68888	488nm and 640nm lasers, 6 parameters: FSC, SSC, BL1 (530/30), BL2 (572/28), BL3 (675/30), RL1 (765/30), with additional laser, automatic plate loader for High Throughput Screening and additional detectors
ABI Step One Plus Real Time PCR System	The Applied Biosystems StepOne™ and StepOnePlus™ Real-Time PCR Systems use fluorescent-based polymerase chain reaction (PCR) reagents to provide: • Quantitative detection of target nucleic acid sequences (targets) using real-time analysis. • Qualitative detection of targets using post-PCR (endpoint) analysis. • Qualitative analysis of the PCR product (achieved by melt curve analysis that occurs post-PCR). Data production: 1. Excitation – The instrument illuminates all wells of the reaction plate within the instrument, exciting the fluorophores in each reaction. 2. Emission – The instrument optics collect the residual fluorescence emitted from the wells of the reaction plate. The resulting image collected by the device consists only of light that corresponds to the range of emission wavelengths. 3. Collection – The instrument assembles a digital representation of the residual fluorescence collected over a fixed time interval. The StepOne™ software stores the raw fluorescent image ...	Responsible: Bene Pál Krisztián Organizational unit: University of Debrecen; Faculty of Medicine; Department of Immunology E-mail: krisztian.bene@med.unideb.hu	- 96-well platform (0.1 ml/well plate) - VeriFlex™ sample blocks: The StepOnePlus instrument contains six independently thermally regulated VeriFlex™ blocks to help you optimize your thermal cycling conditions. You can set a different temperature for one or more of the VeriFlex blocks, creating up to six different zones for samples, or you can set the same temperature for each of the VeriFlex blocks. - The StepOnePlus™ instrument features a four-color filter set that supports the following dyes:
Tecan FREEDOM EVO 150 liquid handling robot	-	Responsible: Dr. Hegedűs Csaba Organizational unit: University of Debrecen; Faculty of Medicine; Institute of Medical Chemistry E-mail: hcsaba@med.unideb.hu Phone: +36 (52) 411-717/54349	- 2 shakers: shaker module for 2 plates - Measurement of liquids: - 8-channel pipetting head: - can work with fixed and disposable pipette tips - Different sizes of the latter cover the spectrum from 1 to 1000 μl. - 96-well pipetting head with fixed pipette tips
Prometheus NT.48, nano differential scanning fluorimetry/	A fast, label-free method that can monitor protein stability and heat-induced structural changes in up to 48 samples simultaneously. Suitable for quality control and quality assurance in the development of protein formulations.	Responsible: Márton Zsolt Organizational unit: University of Debrecen; Faculty of Medicine; Institute of Medical Chemistry E-mail: zsolt.marton@med.unideb.hu Other contact: Dr. Bécsi Bálint, bbalint@med.unideb.hu	Power supply: 90-264 VAC± 10% 47-63 Hz, 230 VA, for indoor use, 12 VDC, 10 A max, Temperature control unit: with settings between 15-95 °C. Noise level: 64 dB max. UV- LED unit built-in: provides 285 nM wavelength UV light (with laser intensity).
Sorvall LYNX 4000	The Sorval LYNX 4000 high performance centrifuge is capable of performing preparative centrifugations with up to 4 L tubes at higher gravity settings. The instrument automatically locks the rotor on insertion, recognises the type and offers the available settings for operation.	Responsible: Kónya Zoltán Organizational unit: University of Debrecen; Faculty of Medicine; Institute of Medical Chemistry E-mail: konya.zoltan@med.unideb.hu Phone: +36 (52) 518-600/61174 Other contact: Márton Zsolt zsolt.marton@med.unideb.hu 61182	Sorvall LYNX 4000, 380 / 400 V, Connector: IEC60309 16A-6h 5 pin red (3P + N + PE), 380 / 400 V, Ambient heat load per hour: 2.0 kWh / 6,830 Btu / 7,200 kJ, Speed control: 500 rpm-24000 rpm, Max rcf for suitable rotor: 68905 g, Noise level: 59-61 dB, Adjustable internal temperature: -10 - +40°C, Weight: 311 kg
Cellular metabolism_equipment and sample preparation	The Seahorse XF96 analyser can simultaneously measure oxygen consumption (OCR) and extracellular acidification rate (ECAR) of scalar cells, cells in suspension, isolated mitochondria and non-malignant samples in 96-well plate format. It can analyse cells in culture and ex-vivo samples. The OCR data can be used to infer mitochondrial function of cells and the ECAR data can be used to infer glycolytic activity. The use of agents that inhibit different respiratory complexes in the mitochondria allows the investigation of different components of the electron transport chain (mitochondrial stress test), and the inhibition of glycolysis (glycolysis stress test) allows the investigation of changes in the energy balance of cells. The instrument allows phenotyping and dose-response relationships to be explored and the results can be viewed immediately using Windows-compatible software (Wawe software).	Responsible: Márton Zsolt Organizational unit: University of Debrecen; Faculty of Medicine; Institute of Medical Chemistry E-mail: zsolt.marton@med.unideb.hu Other contact: Dr. Bécsi Bálint, bbalint@med.unideb.hu	- Compatible with scanning or suspension cells, isolated mitochondria, non-malignant samples - Possible injection of 4 independent substances per wave with automatic mixing - Automatic calculation of OCR and ECAR - Simultaneous measurement of OCR and ECAR in the same well - Real-time detection, live cell responses - Windows-compatible software
NovoCyte 3000 flow cytometer	The NovoCyte 3000 flow cytometer is suitable for the detection of fluorescently labelled cells. Users benefit from the automatic amplification and autocompensation options. Automatic and manual compensation is possible before, during and after data collection. In addition to FSC and SSC, the instrument is capable of detecting 13 fluorescent channels. Sample volumes range from 10 µl to 5 ml, with the possibility to measure small sample volumes (minimum sample volume 50 µl). Detection is performed in a range of 7 orders of magnitude. The NovoExpress software allows data evaluation and the generation of publication-quality plots. The data can be exported to other evaluation programs. Translated with DeepL.com (free version)	Responsible: Dr. Kovács Katalin Organizational unit: University of Debrecen; Faculty of Medicine; Institute of Medical Chemistry E-mail: kovacs.katalin@med.unideb.hu Phone: +36 (20) 669-6074 Other contact: Márton Zsolt zsolt.marton@med.unideb.hu 61182	Small bench-top cytometer with 3 solid phase lasers (violet laser - 405 nm, blue laser - 488 nm, red laser - 640 nm), thermoelectric cooling system. Detection is performed with photoelectron multipliers. It is suitable for the detection of FSC, SSC and 13 fluorescence channels. The injector sample injector allows manual and automatic sample injection, the automatic sample injector is compatible with 12x75 mm tubes and 96-well plates. The operating functions (start, wash, stop) are automatic.
Odyssey CLx Infrared Imaging System	The LI-COR Odyssey CLx imaging instrument enables reproducible western blotting. It also has the advantage of being able to fluorescently detect two proteins simultaneously, so that the phosphorylation of proteins can be studied within the same sample. Detection is performed with a highly sensitive photodiode stack as opposed to a conventional camera.	Responsible: Dr. Tar Krisztina Organizational unit: University of Debrecen; Faculty of Medicine; Institute of Medical Chemistry E-mail: tark@med.unideb.hu Phone: +06 (52) 412-345 Other contact: Márton Zsolt zsolt.marton@med.unideb.hu 61182	Technical parameters of the fluorescence gel documentation and image analysis device:Excitation source: point source laser, Laser lifetime: at least 40,000 hours, Laser source: min. 2 solid phase diode lasers, Lasers: 700 and 800 nm, Detection mode: photodiode bundle; dynamic range 4 log (manual) or 6 log (autoscan mode). Focussing range: the microscope can be adjusted from 0 mm to 4 mm above the scanning bed to obtain the best signal-to-noise ratio. Weight: 33 kg
Tecan Spark 20M multimode plate reader	Specifications of the measurement methods: o Absorbance  Monochromator  Measuring range: 230-999 nm or wider  Dynamic range: 0-4 OD o Fluorescence intensity  Monochromator  lower and upper reading  Measuring range: 250-850 nm o Luminometry  full wavelength range and possibility to set specific wavelength values o Alpha screen o TRF o HTRF o FP	Responsible: Dr. Hegedűs Csaba Organizational unit: University of Debrecen; Faculty of Medicine; Institute of Medical Chemistry E-mail: hcsaba@med.unideb.hu Phone: +36 (52) 411-717/54349	Multimode plate reader, capable of measuring Absorbance, Fluorescence intensity, Luminometry, Alpha screen, TRF, HTRF, FP
Leica TCS SP8 confocal microscope	The Leica TCS SP8 confocal microscope is suitable for high-resolution confocal imaging, primarily of fixed specimens. Thanks to the four laser sources, it is possible to image 4 different fluorescence markings on a single sample._The images are evaluated using the Leica Application Suite X software included with the instrument. The software provides the possibility to measure the fluorescence intensity within each channel and to measure the colocalization of different markings.	Responsible: Dr. Kókai Endre Organizational unit: University of Debrecen; Faculty of Dentistry; Division of Dental Biochemistry E-mail: ekokai@med.unideb.hu Phone: +36 (52) 412-345/61179 Other contact: Márton Zsolt zsolt.marton@med.unideb.hu 61182	Leica TCS SP8 confocal microscope includes 4 solid phase laser sources (400-700 nm) and 4 objectives (5x, 10x, 40x, 63x)
ECIS Z Theta	Electric Cell-Substrate Impedance Sensing, (ECIS) is an impedance-based method to quantitatively measure cell movement and morphological changes in the nanometer range. This ECIS technique allows the adhesion and migration of living cells to be monitored in real time under in vitro conditions. The method is also often used to monitor dynamic changes in cells in response to physical, chemical or biological stimuli.	Responsible: Márton Zsolt Organizational unit: University of Debrecen; Faculty of Medicine; Institute of Medical Chemistry E-mail: zsolt.marton@med.unideb.hu Other contact: Dr. Bécsi Bálint, bbalint@med.unideb.hu	Complex impedance Z, R and C, 16 measurement locations, multi-frequency measurement: 50 Hz - 100 kHz, single frequency 5 point/sec, Wounding / Electroporation, frequency accuracy: 0.002 %
Monolit NT.115, micro scale thermophoresis	The instrument allows rapid analysis of the interactions of biomolecules (proteins, peptides, small molecules, nucleic acids, lipids), even with unpurified preparations of proteins. It can also be used in glycobiology.	Responsible: Márton Zsolt Organizational unit: University of Debrecen; Faculty of Medicine; Institute of Medical Chemistry E-mail: zsolt.marton@med.unideb.hu Other contact: Dr. Bécsi Bálint, bbalint@med.unideb.hu	Power supply: 90-264 VAC ± 10% 47-63 Hz, 230 VA, for indoor use, Infrared laser: 1475 nm ± 15 nm, power: 120 MW maximum, Class 1 laser. Temperature control unit: temperature setting between 22-45 °C can be specified. Noise level: max 64 dB
Monolit NT.LabelFree, micro scale thermophoresis	The instrument allows rapid analysis of the interactions of biomolecules (proteins, peptides, small molecules, nucleic acids, lipids). Protein labelling is not required.	Responsible: Márton Zsolt Organizational unit: University of Debrecen; Faculty of Medicine; Institute of Medical Chemistry E-mail: zsolt.marton@med.unideb.hu Other contact: Dr. Bécsi Bálint, bbalint@med.unideb.hu	Power supply: 90-264 VAC ± 10% 47-63 Hz, 230 VA, for indoor use, 12 VDC, 5 A max, 2.4 A normally Infrared laser: wavelength: 1475 nM, power: 120 mW, class 1 laser. Temperature control unit: temperature adjustable between 22-45 °C. Noise level: max 64 dB
Biacore 3000	The instrument is capable of detecting molecular interactions and determining binding parameters even for small sample volumes. It does not require any modification of the partners to perform the experiments. One partner is immobilised on the surface of a thin gold film and a solution of the other partner is flowed over the surface to be tested. The change in resonance signal obtained from the binding is used for the evaluation.	Responsible: Márton Zsolt Organizational unit: University of Debrecen; Faculty of Medicine; Institute of Medical Chemistry E-mail: zsolt.marton@med.unideb.hu Other contact: Dr. Bécsi Bálint, bbalint@med.unideb.hu	100-120 V~ / 220-240 V~ switched 47-63 Hz, 580 VA max Fuses 2 × T6.25A / 2 × T3.15A, LED diode: 760 nm, Temperature control unit: adjustable between 4-40°C. Built-in peristaltic pumps. Automatic sampling unit. Flow cells. Detector unit.
ITC 200	The instrument is capable of directly determining the thermodynamic parameters of molecular interactions. It measures the thermal changes that occur during the interaction. The rearrangement of the secondary interactions is monitored by heat release or heat loss. The instrument mixes the partners under continuous stirring while compensating the temperature of the measuring cell to a specified reference cell temperature according to the specified parameters. The measuring cell contains one partner, the stirring injector contains the other partner.	Responsible: Márton Zsolt Organizational unit: University of Debrecen; Faculty of Medicine; Institute of Medical Chemistry E-mail: zsolt.marton@med.unideb.hu Other contact: Dr. Bécsi Bálint, bbalint@med.unideb.hu	power: 100-240 V AC, 50/60 Hz, 70 W, 4 A. The instrument is equipped with: cell washing unit, solution storage tubes (waste, methanol, water, solution), automatic injection unit with syringe needle and necessary electronics, syringe washing and drying unit, sample holder.
Tecan FREEDOM EVO 150 liquid handling robot	-	Responsible: Dr. Hegedűs Csaba Organizational unit: University of Debrecen; Faculty of Medicine; Institute of Medical Chemistry E-mail: hcsaba@med.unideb.hu Phone: +36 (52) 411-717/54349	- Shaker: shaker module for 2 plates - 37°C incubator: capable of holding 6 plates - Liquid tracing: - 8-channel pipetting head: - Can work with fixed and disposable pipette tips - Different sizes of the latter cover the spectrum from 1 to 1000 μl. - 96-well pipette tips - "pin tool": small (nanolitre scale) volumes
ABi Prism 310 Genetic Analiser	A szekvenáló futás kapilláris elfo alapján történik. A szekvenálandó mintát egy PCR reakcióban fluoreszcensen jelölt dideoxi-NTP-kel kell jelölni, a reakcióban, a láncterminálás következtében különböző méretű jelölt fragmentek keletkeznek, amelyek a kapilláris elfo során elválnak. Az érzékelő ablakhoz érkező jelölt fragmentet lézer gerjeszti, a fluoreszcens jelet egy CCD kamera fogadja.	Responsible: Dr. Kusza Szilvia Organizational unit: Mezőgazdaság-, Élelmiszertudományi és Környezetgazdálkodási Kar; Állattudományi, Biotechnológiai és Természetvédelmi Intézet; Állatgenetikai Laboratórium E-mail: kusza@agr.unideb.hu Other contact: Kusza Szilvia (06-20-537-2705), Sebők Tibor (+36203903644, +3614718989) Tibor.Sebok@ eur.appliedbiosystems.com	The laboratory offers the possibility to analyse DNA fragments labelled with fluorescent dyes, such as SNP detection, STR and AFLP applications, and microsatellite analysis. Using multiple stains simultaneously, up to 300-400 samples per day can be analysed using the software provided.
Farinograph/Resistograph	The Farinograph's kneading unit prepares the dough under defined and reproducible conditions. The measuring principle is based on the fact that the instrument visualises the mechanical resistance of the dough against the rotating blades of the kneader. The torque proportional to this is a measure of the viscosity and consistency of the dough.	Responsible: Pákozdi Hajnalka Organizational unit: University of Debrecen; Faculty of Agricultural and Food Sciences and Environmental Management; Agricultural Instrumentation Centre E-mail: pakozdy@agr.unideb.hu Phone: +06 (52) 508-444/88509	The farinograph is used to test the kneading properties of flour and flour mixtures in order to determine the quality of the flour and the properties of the dough made from it.
Microplate reader	This multifunctional microplate reader allows a wide range of laboratory tests to be carried out, including fluorescence intensity measurements, full UV/VIS spectra, BRET, FRET, fluorescence polarization real-time kinetic measurements. Instrument with intuitive control and data analysis software.	Responsible: Gálné Remenyik Judit Organizational unit: University of Debrecen; Faculty of Agricultural and Food Sciences and Environmental Management; Institute of Food Technology E-mail: remenyik@agr.unideb.hu Phone: +36 (52) 518-600/68298	Measuring modes: endpoint and kinetic determinations, spectral scanning, 6-1536-well plate measurement, UV/VIS absorbance, fluorescence and luminescence; spectral range: 220-1000 nm; solvent injection during measurement, sample temperature adjustable up to 3-65 o C
Olympus BX61 light, phase contrast and fluorescent microscope	A motorised, upright research microscope that is ideal for the examination of native or stained preparations.	Responsible: Dr. Máthé Endre Organizational unit: University of Debrecen; Faculty of Agricultural and Food Sciences and Environmental Management; Institute of Food Technology E-mail: endre.mathe18@mailbox.unideb.hu Phone: +36 (30) 530-6075	20X, 40x, 60x Plan Fluorite lenses, XC50 5 MP cooled (Peltier) snes 2/3" CCD camera, CS-DI-V1 cellSens Dimensions Version 1.11 Imaging and measurement software
Olympus MVX10 light and fluorescent macroscope	stereomicroscope	Responsible: Dr. Máthé Endre Organizational unit: University of Debrecen; Faculty of Agricultural and Food Sciences and Environmental Management; Institute of Food Technology E-mail: endre.mathe18@mailbox.unideb.hu Phone: +36 (30) 530-6075	1x Planapochromat lens, Olympus DP73 cooled colour 1/1.8" CCD camera, CS-EN-V1 cellSens Entry Version 1.11 imaging and measurement software
Ultra Performance Liquid Chromatography	The ultra-high performance liquid chromatograph (UHPLC) can be used for high sensitivity and high resolution separations at extremely high pressures (1000 bar) on stationary phases with a particle diameter below 2 µm. A major advantage is that the resolution of the separation is not degraded while the analytical time is reduced.	Responsible: Gálné Remenyik Judit Organizational unit: University of Debrecen; Faculty of Agricultural and Food Sciences and Environmental Management; Institute of Food Technology E-mail: remenyik@agr.unideb.hu Phone: +36 (52) 518-600/68298	6170 Binary Pump gradient type: two-component high pressure gradient; max pressure: 1400 MPa; 6270 Auto Sampler: max pressure: 1400 MPa; injection volume: 0.1-20µl; 6310 Column thermostat: column space heating: 4-90 0C; 6430 DAD : light source D2; wavelength range: 190-650 nm; detector type: 1.024 bit
Liquid Chromatography/Mass Selective Detector	Mass spectrometry is a technology for the study of matter based on the formation of gaseous ions, which can be separated, detected and characterised by mass and charge. It is a technology for the detection of very small amounts of matter. The detection process consists of the following steps: ionisation (electrospray ionisation); fragmentation; ion selection (m/z) using a quadrupole mass analyser; mass spectrum generation.	Responsible: Gálné Remenyik Judit Organizational unit: University of Debrecen; Faculty of Agricultural and Food Sciences and Environmental Management; Institute of Food Technology E-mail: remenyik@agr.unideb.hu Phone: +36 (52) 518-600/68298	mass range: 20-1000 m/z; resolution: 0,7 Da (609 reserpins) sensitivity: S/N ≥100; ion source: ESI (electrospray ionization); mass spectrometer: quadrupole; mode: scan/SIM; polarity: positive/negative mode; scan speed:5000-10000 Da/s
Inductively coupled plasma optical emission spectrometer	ICP-OES is suitable for the qualitative and quantitative determination of macro- and microelement content in liquid (or liquid-phase) samples. It is capable of simultaneous determination of approximately 70 elements simultaneously, excluding organogenic elements, halogens and noble gases, and radioactive elements. The determination is based on the optical emission of the elements in high temperature plasma (6000-8000 K). The detection limit of the instrument is in the range of µg/L to mg/L depending on the element under test. The instrument has a maximum measuring capacity of 100 samples/8 hours.	Responsible: Nyeste Erika Julianna Organizational unit: University of Debrecen; Faculty of Agricultural and Food Sciences and Environmental Management; Institute of Food Science E-mail: Phone: +06 (52) 508-444/88010 Other contact: nyeste@agr.unideb.hu	Technical specifications: power output 950-1350 W, RF generator at 27 MHz, CID solid-state detector, Echelle optical system, wavelength range 166-847 nm, axial and/or radial observation. Argon consumption less than 15 L/min, sample requirement about 5 ml liquid. After sample preparation, instrument warm-up and calibration, the sample analysis time is 3-5 minutes.
Inductively coupled plasma mass spectrometer (Thermo Scientific X-Series II ICP-MS)	ICP-MS is suitable for the qualitative and quantitative analysis of the micro- and trace element content of liquid (or liquid-soluble) samples. It is also suitable for the quasi-simultaneous determination of approximately 80 elements, excluding organogenic and radioactive elements and noble gases, and for the determination of the concentration and ratio of individual isotopes of these elements. The measurement is based on the mass/charge separation of the isotopes of the elements, the ions required for which are formed in the high temperature (6000-8000 K) plasma. The instrument is capable of achieving lower detection limits than conventional measurements by using collision and reaction cells. The detection limit of the instrument is in the range of pg/L to µg/L depending on the isotope under test.	Responsible: Soós Áron Organizational unit: University of Debrecen; Faculty of Agricultural and Food Sciences and Environmental Management; Institute of Food Science E-mail: soosaron@gmail.com Phone: +05 (52) 508-444/88170	Technical description of the instrument: power output 1000-1600 W, single quadrant mass spectrometer with a mass range of 2-260 amu. Argon consumption is less than 16 L/min, with a sample requirement of approximately 1 to 5 ml of liquid. Sample analysis time is 2-6 minutes after sample preparation, warm-up and calibration, depending on the number of isotopes tested. Impact and reaction cells can be used with H2:He, He or NH3:He gases using flow rates of 0-10 ml/min.
iCAP 7400 Duo View ICP-OES spektrometer	The iCAP 7400 Duo View ICP-OES spectrometer is currently validated for 44 elements on soil, plant material, water, organic manure and food matrices.	Responsible: Dr. Pusztahelyi Tünde Organizational unit: University of Debrecen; Faculty of Agricultural and Food Sciences and Environmental Management; Agricultural Instrumentation Centre E-mail: pusztahelyi@agr.unideb.hu Phone: +06 (52) 508-444/88515	Concentric glass nebulizer introduction kit: glass cyclonic spray chamber, semi-demountable EMT torch; 1.5 mm bore quartz center tube (Radial); 2 mm bore quartz center tube (Duo), Plasma gas: mass flow control, 0-20 L/min, Spectral bandpass: 7 pm at 200 nm, 166 – 847 nm range; Detector: High performance solid state CID86 chip
Inductively coupled plasma optical emission spectrometer	ICP-OES is suitable for the quantification of the macro- and microelement content of liquid (or liquid-phase) samples, based on the optical emission of elements in high temperature (6000-8000 K) plasma. The instrument has a measuring capacity of up to 150 samples/8 hours.	Responsible: Dr. Pusztahelyi Tünde Organizational unit: University of Debrecen; Faculty of Agricultural and Food Sciences and Environmental Management; Agricultural Instrumentation Centre E-mail: pusztahelyi@agr.unideb.hu Phone: +06 (52) 508-444/88515	The Optima 3300 is a dual detector device. Axial and/or radial monitoring is possible. The scanable wavelength range is 165-782 nm. The sample requirement is approximately 5 ml of liquid. After sample preparation, instrument warm-up and calibration, the sample analysis time is 3-5 minutes. It is currently configured for Si determination only.
contiflow analyzer	The FIAstar 5000 is a fully automated system for measuring ammonium, nitrate/nitrite, phosphate and total phosphorus. It is equipped with a built-in DDW sensor, peristaltic pump, thermostat (35°C- 120°C). The whole system is controlled by FIAstar 5000 SiFIA software. The instrument is ready for analysis 30 minutes after start-up. Analysis time per sample is 40-70 seconds. Reagent consumption: 0.3-2 ml. The modules include a digital dual wavelength photometer with automatic background correction. Absorption interval 0-2,5 AU. Resolution 0,001AU. 120 samples can be placed in the sample changer at the same time.	Responsible: Dr. Pusztahelyi Tünde Organizational unit: University of Debrecen; Faculty of Agricultural and Food Sciences and Environmental Management; Agricultural Instrumentation Centre E-mail: pusztahelyi@agr.unideb.hu Phone: +06 (52) 508-444/88515	The instrument is suitable for measuring different forms of nitrogen (nitrate, nitrite, ammonia) and phosphorus in soil and water samples.
microwave digestor	Most elemental analysis measurements require dissolved samples and therefore the procedure requires sample preparation. As elemental analysis techniques become more sensitive, even more emphasis must be placed on the correct preparation of samples. It is widely recognised that microwave destructive analysis is the most suitable technique for sample preparation for AA, ICP-OES and ICP-MS techniques. With a closed sample preparation system, by combining the three factors mentioned above, the heating process can be kept completely under control, thus preventing sample loss. The direct control of the heating and the rapid variability of the heating process are one of the main advantages of microwave heating over conventional heating.	Responsible: Pákozdi Hajnalka Organizational unit: University of Debrecen; Faculty of Agricultural and Food Sciences and Environmental Management; Agricultural Instrumentation Centre E-mail: pakozdy@agr.unideb.hu Phone: +06 (52) 508-444/88509	The Milestone Ethos Plus is a microwave sample preparation system with an advanced vessel (MDR), a sensitive chemical sensor (Q.P.) and Windows-based Easywave software. These allow you to digest solid and liquid samples safely and without loss.
varioMax CNS	The varioMAX CNS Elemental Analyser is a fully automatic instrument for rapid quantitative analysis of CNS elements, capable of simultaneous determination of CNS elements from a given sample in two modes/measurement modes. The varioMAX CNS is exclusively intended for elemental analysis of combustible samples or sample quantities that can be controlled depending on the mode. The analyser works on the principle of high temperature catalytic tube combustion with the introduction of oxygen. The gases produced as combustion products are purified from interfering foreign gases. The respective measurement components required are separated by means of specific adsorption columns, after which the thermal conductivity detector performs the determination. Due to its nature, it is only economical to use for large sample quantities (over 200 samples).	Responsible: Dr. Pusztahelyi Tünde Organizational unit: University of Debrecen; Faculty of Agricultural and Food Sciences and Environmental Management; Agricultural Instrumentation Centre E-mail: pusztahelyi@agr.unideb.hu Phone: +06 (52) 508-444/88515	WLD detector, RS 232/V24 safety extra-low voltage according to DIEN IEC 380/VDE 0806/8.81, Power consumption: 0.8 kW, Power requirement: 1.6 kVA, German or English menu-driven status display during analysis, real-time graphics
GC-MS/MS	The instrument is equipped with a gas chromatograph where the components of the sample are separated. The separated components undergo ionisation, which causes them to split into different fragments, typical of the material, and are then transferred to an ion trap in the MS detector, which then separates them by mass/charge and finally to an electron multiplier detector, which gives a signal corresponding to the intensity. This provides a qualitative and, using a suitable calibration line, a quantitative analysis.	Responsible: Dr. Pusztahelyi Tünde Organizational unit: University of Debrecen; Faculty of Agricultural and Food Sciences and Environmental Management; Agricultural Instrumentation Centre E-mail: pusztahelyi@agr.unideb.hu Phone: +06 (52) 508-444/88515	The instrument includes a gas chromatograph, a vacuum system providing a sufficiently low pressure, an MS/MS detector and a data processing unit.
automatic amino acid analyzer	The amino acid analyser is capable of measuring the protein content of the analysed feed, finished food and food raw materials.	Responsible: Dr. Pusztahelyi Tünde Organizational unit: University of Debrecen; Faculty of Agricultural and Food Sciences and Environmental Management; Agricultural Instrumentation Centre E-mail: pusztahelyi@agr.unideb.hu Phone: +06 (52) 508-444/88515	Sensitivity: 10-15 pmol, Concentration range: 15 pmol-200 µmol, Reproducibility at 10nmol: better than 1.0%, Columns, metal size: 4.0x70-250mm (for hydrolyzed amino acids), 4.0x150mm (for free amino acids), Heating temperature range: 25-90°C, Pump system: 6 parts programmable, Flow: 0.01-7.5 ml/min, Pressure: 0-25MPa, Automatic cooled sample dispenser, 6 channel vacuum gas vent, Sample volume with "A" cassette: 40x1.5ml, Dual channel photometer: 440 and 570 nm, Cell volume: 5µl
Fluorescent microscope – Zeiss Axioplan 2	The Zeiss Axioplan fluorescence microscope is a microscope equipped with optimized excitation and emission filter systems, a CCD (AxioCamICc1; Color, 1.4MP) camera and image analysis software for a wide range of tasks. Besides the acquisition of qualitative, high quality fluorescence images, quantitative analysis is also possible. The microscope is equipped with objectives of different magnifications (10x,20x,40x, 63x and 100x). The computer-controlled ISIS 5.0 Software provides the background for high quality imaging, as well as for editing and preparing fluorescence images for publication.	Responsible: Dr. Ádám Balázs Organizational unit: Népegészségügyi Kar; Megelőző Orvostani Intézet; Munkaegészségtani nem önálló Tanszék E-mail: adam.balazs@sph.unideb.hu Phone: +06 (52) 512-765/77157 Other contact: balazs.margit@sph.unideb.hu, adam.balazs@sph.unideb.hu, +36-52-512-765/77151, 77157	The Zeiss Axioplan 2 is an upright epi-fluorescent microscope equipped with a 100 W mercury lamp and a CCD camera (IMAC-CCD, Computer Systeme, Germany) connected to a computer on which image analyses systems are installed such as Comet Imager v.2.2.1. and ISIS 5.1 for FISH and chromosomal CGH Software (MetaSystems GmbH, Germany)
Leica Laser Micro Dissection Microscope and Model VSL-337ND-S Powered by Pulsed UV, Air-Cooled, Nitrogen Laser System	The microscope is a fully motorized microdissection system that can be used in a closed, contamination-free manner to isolate homogeneous, high-purity individual cells or cell groups from native, histologically stained or fluorescently labeled fresh-frozen or archived tissue sections and live cell cultures using a laser. The excised tissue pieces are then collected directly in the sample buffer by gravity. The instrument is also equipped with a 100W Hg vapour lamp for the detection of fluorescent labels on 4 channels. The UV laser beam is supplied by a high energy nitrogen gas excitation unit. The UV laser has a wavelength of 337.1nm, a maximum frequency of 30Hz, a pulse width of 4nsec, an energy of 300μJ and a beam spread of 0.3mrad. The Leica LMD analysis software is user-friendly and easy to use. In addition to quick adjustment of the laser beam parameters, it can be controlled automatically or manually.	Phone: +36 (30) 358-7385 Other contact: Szakácsi János, szakacsi@belklinika.com, +36 303587385	https://www.leica-microsystems.com/fileadmin/downloads/Leica%20LMD7000/Brochures/Leica_LMD6500-7000-Brochure_en.pdf; https://www.leica-microsystems.com/products/light-microscopes/p/leica-lmd7/specification/
Zeiss LSM 700 Laser scanning microscope	A Zeiss LSM 700 microscope for general use, equipped with all the tools needed for high-resolution imaging. Excitations between 405 and 639 nm are achieved with 4 lasers. A series of mirrors in the scanning module directs the excitation light beams into the optical axis of the system. The microscope's emission system (variable secondary dichroic (VSD) beamsplitter) ensures simultaneous application of fluorophores in samples labelled with fluorescent dyes with significant spectral overlap. The VSD offers a high degree of flexibility in detection. The microscope system features a motorized precision pinhole for maximum reproducibility. The aperture and the position of the precision pinhole can be continuously and automatically adjusted. The objective lenses (5x, 10x (phase contrast), 20x (DIC), 40x (adjustable working distance), 63x (DIC)) allow a wide range of magnification.	Responsible: Dr. Bárdos Helga Organizational unit: Népegészségügyi Kar; Megelőző Orvostani Intézet E-mail: bardos.helga@sph.unideb.hu Phone: +06 (52) 512-768/77154	https://www.mikroskop.com.pl/pdf/LSM700_1.pdf
Lipidyzer	The instrument consists of a Sciex QTRAP 5500 tandem mass spectrometer, a high-performance liquid chromatograph with automatic injector, and the associated computer control and data processing system. The measuring process is fully automated, with 105 samples being placed in the automatic injector.	Responsible: Dr. Szücs Sándor Organizational unit: Népegészségügyi Kar; Megelőző Orvostani Intézet E-mail: szucs.sandor@sph.unideb.hu Phone: +36 (52) 512-765/77152 Other contact: Dr. Ádány Róza, adany.roza@sph.unideb.hu, +36-52-512-765/77148	Three-quadrant mass spectrometer, two-quadrant analyser, one collision cell, electrospray ionisation, scanning types: mother ion, daughter ion and neutral loss scanning
LightCycler® 2.0 Real-Time PCR	The LightCycler® 2.0 instrument allows amplification of 32 PCR products simultaneously, in real time and under online supervision, with six different sensor channels in multiplex experiments. The LightCycler® 4.1 software collects fluorescence data from all six channels in each cycle and displays it instantly, allowing early stopping of PCR if signal levels are adequate or extending them if signals are too low. Amplification takes place in specially designed reaction capillaries with excellent surface-to-volume ratios that allow extremely fast thermal transfer, facilitating high-speed thermal cycling. The combination of LightCycler® capillaries and air-controlled temperature regulation allows the complete 35-cycle run to be performed in 30 minutes (with 20 µl capillaries) to 60 minutes (with 100 µl capillaries).	Responsible: Dr. Fiatal Szilvia Organizational unit: Népegészségügyi Kar; Megelőző Orvostani Intézet E-mail: fiatal.szilvia@sph.unideb.hu Phone: +36 (52) 512-765/77148 Other contact: adany.roza@sph.unideb.hu, 77166	- 28.0 cm x 38.5 cm x 50.5 cm - 22 kg - 32 samples - 20 µl - 100 µl - sensors: 530, 560, 610, 640, 670, 710 nm - Run time: <30 minutes for 35 samples - Heater/cooler: 0.1-20 °C/s - temperature accuracy: ± 0.4°C
LightCycler ® 480 Real-Time PCR	The LightCycler® 480 system is a high-throughput, flexible transfer qPCR platform (interchangeable 96- or 384-well plates can be used) that provides a variety of methods for gene(s) detection, gene expression analysis, analysis of genetic variation and detection of pathogens. This versatile tool is ideal for rapid and high precision work.	Responsible: Dr. Fiatal Szilvia Organizational unit: Népegészségügyi Kar; Megelőző Orvostani Intézet E-mail: fiatal.szilvia@sph.unideb.hu Phone: +36 (52) 512-765/77148 Other contact: adany.roza@sph.unideb.hu, 77166	-
Gas chromatograph/mass spectrometer	The instrument consists of an HP 6890 gas chromatograph, an HP 5973 mass selective detector, an Agilent 7683 automatic injector, and the associated computer control and data processing system. The measuring process is fully automated, with 8 samples being placed in the automatic injector.	Responsible: Dr. Szücs Sándor Organizational unit: Népegészségügyi Kar; Megelőző Orvostani Intézet E-mail: szucs.sandor@sph.unideb.hu Phone: +36 (52) 512-765/77152 Other contact: Dr. Ádány Róza, adany.roza@sph.unideb.hu, +36-52-512-765/77148	Quadrupole mass spectrometer, electron impact ionisation, scanning types: total ion monitoring, selective ion monitoring
PCR	-	Responsible: Dr. Batta Gyula Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Biotechnology; Department of Genetics and Applied Microbiology E-mail: bagyulajuve@unideb.hu Phone: +36 (52) 518-600/60258	-
Prince-770CE	The capillary electrophoresis device allows the separation of compounds with different charges in a suitable buffer under the effect of voltage. The device can be operated with a variety of buffers. The instrument is most suitable for the separation of known compounds with different structures in high concentrations.	Responsible: Dr. Gonda Sándor Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Biology and Ecology; Department of Botany E-mail: gonda.sandor@science.unideb.hu Phone: +06 (52) 512-900/62634	Capillary electrophoresis device
CombiFlash EZ Prep cromatography system	The CombiFlash EZ prep is a combination of a Flash and a preparative HPLC, where we can use the two options interchangeably in software. The Flash chromatography mode typically allows normal phase, while the HPLC mode typically allows reverse phase preparative separation on a suitable chromatographic load. It is possible to collect all fractions or to collect fractions above a given threshold (UV or MS signal). The instrument can be operated with a variety of prefabricated columns or with its own load. The instrument is best suited for the separation of known compounds with different structures in high concentrations. Export of the chromatogram is possible.	Responsible: Dr. Gonda Sándor Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Biology and Ecology; Department of Botany E-mail: gonda.sandor@science.unideb.hu Phone: +06 (52) 512-900/62634	Flash and HPLC branch. Flow rate range: 5-200 ml/min; Pressure upper limit on HPLC branch: 241 bar (3500 psi); 2-2 solvent branches available for both Flash and HPLC mode (2 component eluents can be mixed at the same time). Automatic sample collection, 150 20 volume tubes can be inserted at the same time. UV detector can be used between 200-800 nm, MS detector (PurIon) can be used between 50-1200 Dalton (positive and/or negative ion mode). 2-6 % of the sample is transferred to MS.
Freeze-dryer Christ Gamma 2-16 LSCplus	The lyophilizer can be used for freeze drying of various solid or liquid products. The device is able to dry large quantities of properly prepared materials on its 8 trays. With a temperature of -85 °C and the materials that make up the apparatus, it is possible to remove not only water but also certain solvent-water mixtures: even organic solvents in limited quantities and qualities. The apparatus is able to dry not only extracts and other liquid samples, but also complete plant parts (e.g. fruits). Temperature and vacuum parameters can be changed in software, so that sample-specific drying can be performed. It is possible to export the data recorded during the measurement.	Responsible: Dr. Gonda Sándor Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Biology and Ecology; Department of Botany E-mail: gonda.sandor@science.unideb.hu Phone: +06 (52) 512-900/62634	Ice condenser: capacity: max. 16 kg, maximum output: 12 kg/24 h, temperature: -85 °C, chamber volume: 30 L; sample holder: 8 shelves system, heatable: max. 60 °C, diameter 375 mm.
Shimadzu HPLC	HPLC typically allows reverse phase separation on a suitable chromatographic load. The instrument can be operated with a range of prefabricated columns. The instrument is best suited for the separation of known compounds with different structures in high concentrations.	Responsible: Dr. Gonda Sándor Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Biology and Ecology; Department of Botany E-mail: gonda.sandor@science.unideb.hu Phone: +06 (52) 512-900/62634	HPLC. Flow rate range: 0.1-10 ml/min; Pressure upper limit on HPLC branch: 400 bar; 4 solvent branches available (up to 4 component eluent mixing). UV detector can be used between 200-800 nm. The column in use can be thermostatted.
Analytical HPLC system with OpenLab softwer	High-pressure isocratic chromatographic system with differential refractive index detector, column thermostat and refrigerated sample feeder for chromatographic measurements and evaluations.	Responsible: Németh Zoltán Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Biotechnology; Department of Biochemical Engineering E-mail: nemeth.zoltan@science.unideb.hu Phone: +36 (52) 512-900/22730	Complete UHPLC system with isocratic pump, built-in degasser, column thermostat with integrated sample dispenser, differential refractive index detector, controller, data logger, data processing system.
Fermenter	With the Biostat® B twin MO - UniVessel® Glass 2L fermentor you can perform microbial fermentations in 2 pcs of 2 litre reusable glass bioreactor vessels. The central control unit allows you to set the mixing speed, pH, DO, temperature and run precisely controlled batch and fed-batch fermentations using the large touch screen display. The Biostat B system is the perfect solution for both process optimisation and small-scale production.	Responsible: Németh Zoltán Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Biotechnology; Department of Biochemical Engineering E-mail: nemeth.zoltan@science.unideb.hu Phone: +36 (52) 512-900/22730	Analogue DO measurement and control, analogue pH measurement and control, pH control by dosing acid and alkali via peristaltic pump, air dosing and control, oxygen dosing and control, mixing measurement and control, temperature control.
UV-VIS Spectrophotometer	The UV-3600 UV-VIS-NIR spectrophotometer is the top of the range of UV-VIS-NIR spectrophotometers. The UV-3600 model is the successor to the UV-3150/3101 and is designed to measure liquid samples, but is also suitable for thin film analysis in certain applications. The instrument is equipped with 3 detectors: a PMT detector for the UV and visible range, and InGaAS and PbS detectors for the infrared range. The InGaAs detector is intended to bridge the gap between the switching wavelengths of the PMT - PbS detectors, where the sensitivity is typically lowest in the full high-sensitivity wavelength range. With a noise of 0.00003Abs at 1500nm wavelength, we achieved the lowest noise level in the world. The UV-3600's UVProbe software includes spectral, quantitative and kinetic functions, as well as a report generator. Multi-part security and tracking features ensure data reliability.A multi-purpose large sample holder and integrating sphere accessories allow for robust and reliable data acq	Responsible: Dr. Csarnovics István Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Physics; Department of Experimental Physics E-mail: csarnovics.istvan@science.unideb.hu Phone: +36 (70) 331-4744	Using a high performance double monochromator, we have achieved extremely low stray light (0.00005% or less at 340 nm) at high resolution (maximum resolution 0.1 nm). The wavelength range 185 - 3300 nm allows measurements in the ultraviolet, visible and near-infrared regions. This allows a wide range of variability in spectroscopic analyses.
Veeco diCaliber Atomic Force Microscope	The combination of atomic scale contact areas and atomic scale resolution give scanning probe microscopes like the diCaliber the ability to probe atomic structures and fundamental interactions between surfaces at the atomic scale; such instruments have thus been sub-categorized as atomic force microscopes (AFMs). The diCaliber is a versitile instrument combining high resolution imaging with small size and flexibility in substrate mounting. In fact, this unique AFM can be placed directly onto virtually any surface of interest, making it particularly well-suited for studying tribological specimens. We have used the unique features of this instrument to: (1) study single asperity frictional interactions in controlled environments (2) study the mechanical and frictional properties of tribofilms (3) integrate AFM and macrotribometry experiments for in-situ surface characterization during sliding (4) study irregular surfaces	Responsible: Dr. Csarnovics István Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Physics; Department of Experimental Physics E-mail: csarnovics.istvan@science.unideb.hu Phone: +36 (70) 331-4744	Compact portable AFM • Scans up to 90 x 90μm with a 10μm Z range • Closed loop x-y scanning and built in x-y translator. • Contact and tapping mode • Powerful analysis software • Isolated anti-vibration table allowing sub-nm resolution.
atomic layer deposition equipment (ALD)	Atomic layer deposition (ALD) is a thin film preparation method based on the sequential application of gas phase chemistry. Most ALD reactions use two chemicals, usually referred to as precursors. These precursors react sequentially with the surface of the material, one by one, in a self-limiting manner. In contrast to CVD (chemical vapour deposition), the precursors are never present simultaneously in the reactor, but are introduced into the reaction chamber in a series of successive, non-overlapping pulses. In each of these pulses, the precursor molecules react with the surface, but the reaction is complete when all the reactive sites on the surface are saturated, i.e. the reaction is self-limiting. Consequently, the maximum amount of material deposited on the surface during a single pulse (a so-called ALD cycle) is determined by the nature of the interaction between the precursor and the precursor surface. By varying the number of cycles with high precision (effectively atomic layer	Responsible: Dr. Daróczi Lajos Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Physics; Department of Solid State Physics E-mail: lajos.daroczi@science.unideb.hu Phone: +06 (52) 316-073	Construction of 3D layers (e.g. Al2O3, TiO2, ZnO) thermally and with oxygen plasma up to 1nm thickness
Transmission electron microscope	transmission electron microscope equipped with an energy dispersive X-ray spectrometer	Responsible: Dr. Daróczi Lajos Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Physics; Department of Solid State Physics E-mail: lajos.daroczi@science.unideb.hu Phone: +06 (52) 316-073	200kV accelerating voltage, 0.31nm resolving power
scanning electron microscope (SEM)	scanning electron microscope for general purpose analytical studies (secondary and backscattered electron imaging, energy dispersive X-ray detector)	Responsible: Dr. Daróczi Lajos Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Physics; Department of Solid State Physics E-mail: lajos.daroczi@science.unideb.hu Phone: +06 (52) 316-073	max 30kV accelerating voltage, 1.6 nm resolving power, equipped with energy dispersive X-ray spectrometer
secondary neutral mass spectrometer (SNMS)	The SNMS/SIMS-XPS assembly contains a secondary neutral mass spectrometer, a secondary ion mass spectrometer and an X-ray photoelectron spectrometer (XPS) with a common vacuum system. This arrangement enables the analysis of samples in ultra-high vacuum to be carried out without opening the vacuum chamber during the sample transfer. While mass spectrometry measurements can be performed in the SNMS/SIMS part of the system, the chemical state of elements can be determined in the XPS part. A complete quantitative surface analysis can be performed with high depth resolution (~1 nm) or high lateral distribution.	Responsible: Dr. Daróczi Lajos Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Physics; Department of Solid State Physics E-mail: lajos.daroczi@science.unideb.hu Phone: +06 (52) 316-073	Plasma:Ar, Ne, Kr, Xe; sputtering velocity: ~0.1 nm/s; ion energy: 100 eV - 2 keV; mass spectrometry range: 0-340amu; sensitivity: 1ppm; resolution 1-2nm; sample holder x-y agitation, -180-600oC;
100 L PLC controlled reactor	The reactor allows a range of organic and inorganic reactions to be carried out under controlled conditions. Its operating parameters are controlled by automatic valves mounted on the inlet and outlet stubs. The parameters, temperature, pressure, pH, speed of the mixer motor, mass of the material in the reactor, can be monitored in real time by computer. Both filling and emptying of the reactor are automatic. The reactor can be cooled/heated and the amount of material in the reactor can be monitored by a digital scale. Separation of the reaction mixture is achieved by means of a pressure filter. The inlet can be made through the fixed piping, by means of a PLC controlled pneumatic pump. For the distillation tasks, a tubular heat exchanger is installed on the vapour tube leading out of the reactor. The reflux rate of the distillate is variable. Vacuum distillation is also possible by opening the vacuum valve.	Responsible: Dr. Nagy Miklós Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Applied Chemistry E-mail: nmiklos@unideb.hu Phone: +36 (52) 512-900/22454	The reactor and its fittings are made of acid-resistant steel with a nominal volume of 100 litres. Pressure vessel, pressure variable between full vacuum and 4 bar. Temperature range: -40 to 130 °C. Heating is by steam, cooling by water. A glycol thermostat can be used to maintain the temperature and to reach temperatures below 0 °C. The reaction mixture is mixed by a high-power mixing motor with a speed of 1 rpm between 0 and 400 rpm.
150 L PLC controlled fermentor	The fermentor body is made of pressure and acid-resistant steel and is surrounded by a double wall (so-called duplicator). The pipe fittings in contact with the fermentor interior, the coupling and the air filter are also degermed by high-temperature steam. The sterility of the air introduced into the reactor is ensured by a so-called filter tower with a membrane filter with a pore diameter of 0,2 um. The inoculum cultures are typically introduced into the pilot fermentor in two ways: via a grafting tube (e.g. from Erlenmeyer flasks) or, if a larger amount of inoculum is required, by means of a smaller volume inoculating fermentor. A modern process control system is available to ensure a smooth fermentation process. The following parameters can be measured and controlled: temperature, mixing speed, inlet air volume, fermentation juice chemistry, dissolved oxygen level, internal pressure. In addition, we can measure the power absorbed by the mixer and the fermentor	Responsible: Dr. Karaffa Levente Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Biotechnology; Department of Biochemical Engineering E-mail: levente.karaffa@science.unideb.hu Phone: +36 (52) 512-900/62488 Other contact: Dr. Nagy Miklós miklos.nagy@science.unideb.hu 22454	The fermentation laboratory includes a 150-litre full-volume experimental/semi-commercial fermentor, which is typically used for aerobic fermentations. The apparatus is suitable for the cultivation of different microorganisms with aerobic life-styles (bacteria, yeasts, filamentous fungi) and the production of their metabolites. In industrial biotechnology, similar apparatus are used to model the production conditions and to provide the inoculum required for the production fermentors.
Rotary vacuum evaporator	For industrial distillation in explosion-proof (EX) environments up to 50 litre flask size or for continuous automatic distillation. Specifications One 10 litre evaporating flask One 10 litre collection flask Electric water bath, liftable V fitting (vertical, 1,7 m) Transparent PLASTIC + GLASS (P + G) safety coating Vertical condenser with cooling coils Heating bath: 3600 watt (water or oil) 230V (118716C201)	Responsible: Dr. Nagy Miklós Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Applied Chemistry E-mail: nmiklos@unideb.hu Phone: +36 (52) 512-900/22454	A rotary evaporator is a device used in chemical laboratories for the efficient and gentle removal of solvents. Rotary evaporation is most often and appropriately used for "low boiling point" solvents such as n-hexane or ethyl acetate.
Yokogawa process control software	The Yokogawa system is a graphical process control software that allows pneumatic control of automatic open-close valves under PLC control, metering of individual materials, switching of auxiliary streams on and off, reactor draining, temperature, pressure and pH monitoring. The software has a number of functions: the individual instruments can be called up graphically, trend lines can be used to track changes in the parameters measured on each instrument, screens can be saved, reloaded and printed as required (for basic operating functions, see the HIS User Manual, also available).	Responsible: Dr. Nagy Miklós Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Applied Chemistry E-mail: nmiklos@unideb.hu Phone: +36 (52) 512-900/22454	A rotary evaporator is a device used in chemical laboratories for the efficient and gentle removal of solvents. Rotary evaporation is most often and appropriately used for "low boiling point" solvents such as n-hexane or ethyl acetate.
INSTRON 3366 Universal material tester	The equipment is equipped with an extra high pulling frame and is therefore suitable for testing very tough materials with high relative elongation. The load cell is interchangeable and has a maximum load limit of 10 kN. Mechanical or optical extensometers are not included, but can be fitted as an option. The instrument is controlled by computer using Bluehill software. The softvare includes the following pre-configured test methods (according to specific standards). ASTM D638-14, D790-15e2, D695-10, D882-10, D1894-11e1, D6272-10, ISO 527-2(2012), ISO 527-3(1995), ISO 178(2010), ISO 604(2002).	Responsible: Dr. Deák György Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Applied Chemistry E-mail: deak.gyorgy@science.unideb.hu Other contact: Illyésné Dr. Czifrák Katalin Margit, czifrak.katalin@science.unideb.hu, +36 52 512900/22458	The device can also measure in SI (Metric), US units -Speed range: 0.005-500 mm/min (0.0002 inch/min ÷ 20 inch/min). -Return speed: 600 mm/min (24 inch/min). -Horizontal distance between columns: 420 mm (16.5 inch). - Crosshead displacement: maximum 1637 mm (extra high pulling frame) Accuracy meets or better than: ASTM E-4, BS 1610, DIN 51221, ISO 7500/1, EN 10002-2, JIS B7721, JIS B773, AFNOR A03-501.
BRUKER MALDI-TOF/TOF AUTOFLEX Mass Spectrometer	The mass spectrometer is suitable for determining the molecular weight and molecular weight distribution of high molecular weight polymers, oligomers, proteins and oligopeptides. It can also perform collision-induced dissociation (CID) in MS/MS studies. Sample preparation is performed by the addition of a low molecular weight matrix material, which allows the realisation of soft ionisation. The instrument can be used in both positive and negative ion modes.	Responsible: Dr. Nagy Lajos Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Applied Chemistry E-mail: nagy.lajos@science.unideb.hu Phone: +36 (52) 512-900/22452	The mass spectrometer has an accuracy of 2 ppm (with internal calibration), a resolution of 26 000 FWHM and a sensitivity of 500 fmol, suitable for MS and MS/MS (High enegy CID) analyses with a sensitivity of 1 pmol.
BIOTOF II ESITOF Mass Spectrometer	The ESI, APCI and APPI mass spectrometers with DART ion source can be used for high-resolution MS and MS/MS measurements. LC-MS and LC-MS/MS studies are possible when the mass spectrometer is coupled to HPLC. With the right choice of ion source, it is possible to analyse polar and apolar molecules in both positive and negative ion mode.	Responsible: Dr. Nagy Lajos Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Applied Chemistry E-mail: nagy.lajos@science.unideb.hu Phone: +36 (52) 512-900/22452	The mass spectrometer has an accuracy of 3-5 ppm, a resolution of 15,000 FWHM, a sensitivity of 500 amol and is suitable for MS and MS/MS analyses with a mass accuracy of 3-5 ppm.
Waters High Performance Liquid Chromatograph (HPLC)	A folydékkromatográf lehetővé teszi különböző többkomponensű rendszerek komponenseinek elválasztását fordított vagy normál fázison. A készülékhez kapcsolt törésmutató, fluoreszcenciás és UV-DAD detektorok alkalmasak UV elnyeléssel rendelkező vagy fluoreszcenciásan aktív molekulák detektálására összetett reakcióelegyekből vagy extraktumokból, míg a törésmutató detektor jól alkalmazható oligomerek vagy polimerek analízisére, amelyek nem rendelkeznek UV elnyeléssel.	Responsible: Dr. Nagy Lajos Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Applied Chemistry E-mail: nagy.lajos@science.unideb.hu Phone: +36 (52) 512-900/22452	The liquid chromatograph's sample and column heater is thermostable, allowing two columns to be placed in the instrument at the same time. Detection can be performed by refractive index or fluorescence measurements. And with the UV diode array detector it is possible to record data at several wavelengths simultaneously.
Shimadzu GCMS QP-2010plus gas chromatograph-mass spectrometer	The gas chromatograph is suitable for the analysis of volatile molecules, which can be fragrance components, degradation products, solvent residues and other low molecular weight substances. In addition, volatilised derivatives can be analysed, e.g. fatty acid methyl esters. The instrument is well suited for the separation and mass spectrometric analysis of volatile, low molecular weight components of gas and liquid samples, as the EI ion source allows ionisation of both polar and apolar molecules. In addition to the retention time, the component can be identified by the fragmentation pattern.	Responsible: Dr. Nagy Lajos Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Applied Chemistry E-mail: nagy.lajos@science.unideb.hu Phone: +36 (52) 512-900/22452	The gas chromatograph is equipped with a capillary column, the column space is thermostable and the heating is programmable. The mass spectrometer uses electron ionisation (EI, 70eV) and is equipped with a quadrupole analyser. Automatic injection is possible, the sample holder has 12 places.
Bruker D8 Venture X-ray diffractometer	The Bruker D8 Venture diffractometer system is equipped with two INCOATEC IµS 3.0 microsource radiation sources. Mo Kα radiation (shorter wavelength, λ=0.71 Å) can be used to study organometallic compounds, Cu Kα radiation (λ=1.54 Å) to study protein crystals and organic molecules. For chiral compounds it is important to determine the absolute configuration, for which the Cu Kα source is more suitable. The detector is a high power Photon II CPAD (Charge-integrating Pixel Array Detector), the crystal-detector distance can be varied between 37-240 mm. Goniometer with four-loop κ geometry. The crystal is cooled and heated by an Oxford Cryosystem Cryostream 800+ system in the range 80 - 500 K. The instrument is operated and data is automatically collected by computers. Software tools (APEX3, PROTEUM3, DIFFRAC.EVA, WINGX, OLEX2, CCP4) are available for the evaluation of measurements, allowing the solution of problems such as powder diffraction, small molecule single crystal or powder X-ray	Responsible: Dr. Bényei Attila Organizational unit: University of Debrecen; Faculty of Pharmacy; Dean’s office, Faculty of Pharmacy E-mail: abenyei@unideb.hu	Four-loop X-ray diffractometer system with high-sensitivity field detector and thermostat using liquid nitrogen for sample cooling/heating. Applied wavelength λ=0.71 Å or λ=1.54 Å, air-cooled microsource sources. Video microscope. Sample temperature 80-500K, CMOS sensor based detector, pixel size 96x96 micrometers. Computers, software tools, uninterruptible power supply for operation and structure solution.
JASCO V-770 UV-VIS-NIR	The JASCO V-770 is a dual-beam instrument that can be used to measure absorbance/transmittance/reflectance, spectral recording or quantification in the wavelength range 190 - 2700 nm. Its optical system includes a monochromator, a fixed or adjustable aperture, two light sources, one deuterium lamp for the UV range and a halogen lamp for the visible and near infrared ranges. Detection is performed with a photoelectron multiplier and a lead sulphide detector. The instrument is equipped with an automatic sample holder recognition system. For more information, please visit: https://jascoinc.com/products/spectroscopy/uv-visible-nir-spectrophotometers/	Responsible: Dr. Tircsó Gyula Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Physical Chemistry E-mail: gyula.tircso@science.unideb.hu Phone: +36 (52) 512-900/22374 Other contact: 22389	Optical system: dual beam, with a dual monochromator, 1200 lines/mm for UV/VIS and 300 lines/mm for NIR Light source: deuterium lamp (190-350 nm), tungsten lamp (330-2700) Wavelength range: 190-2700 nm Factory option: 190-3200 nm Wavelength repeatability: ± 0,05 nm UV/VIS ± 0,2 nm NIR Wavelength accuracy: ± 0.3 nm UV/VIS ± 1.5 nm NIR Sp
Minispec MQ60 TD-NMR system	The instrument is used to determine the relaxation properties (T1 and T2 relaxation times) in 1H and 19F "dimensions" of our contrast agent candidates for medical diagnostics and therapy. It is also possible to measure these parameters in a time-dependent and pH-dependent manner, which allows the acquisition of kinetic (formation and dissociation kinetics) and solution equilibrium data (stability of strain and mixed complexes).	Responsible: Dr. Tircsó Gyula Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Physical Chemistry E-mail: gyula.tircso@science.unideb.hu Phone: +36 (52) 512-900/22374 Other contact: 22389	1.4 Tesla, 60MHz TD-NMR system which - a central processor unit with a frequency range of 10-65 MHz with 1 Hz step interval. - broadband transmitter 7.5 MHz: 250 W; 10 MHz: 300 W; 20 MHz: 300 W; 40 MHz: 300 W; 60 MHz: 250 W output power - from a 1.41 T (60 MHz proton Larmor frequency) magnet unit (magnet temperature control with temperature preselection, (35 °C - 45 °C range) with a temperature stability better than 0.01 °C. - from 1H and 19F probes - thermos
YL 9100S prep. HPLC + Corona CAD (PREPARATIVE HPLC SYSTEM)	The YL9100 semi-preparative system is suitable for the highly efficient identification and/or extraction of valuable (necessary) materials for the researcher.	Responsible: Dr. Tircsó Gyula Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Physical Chemistry E-mail: gyula.tircso@science.unideb.hu Phone: +36 (52) 512-900/22374 Other contact: 22389	YL9101S Vacuum degasser - number of channels: 4 - maximum flow rate: 10 ml/min per channel - solvent contact material: TeflonAF and PEEK - YL9110 Quaternary pump (semi-preparative) - dual piston operating in parallel - number of eluents: 4 - gradient training: 4-channel mixing valve - composition precision: < 0,1 % - composition accuracy: < 0,5 % - flow rate: 0,01 - 50 ml/min - flow rate accuracy: ≤± 1 % at 1 ml/min flow rate - flow rate precision: 0,1
LABstar Glove Box – workstation	Glove Box - an instrument used for preparative and catalytic research under inert conditions (excluding oxygen and moisture in the air). It can be used for the synthesis of ligands and catalysts sensitive to oxygen (and humidity) in air, and for the storage of materials requiring absolute inert conditions.	Phone: +36 (30) 358-7385 Other contact: Szakácsi János, szakacsi@belklinika.com, +36 303587385	ready-to-use workstation - with antechamber, vacuum pump, fittings - material: stainless steel, dimensions: 1200 x 780 x 920 mm - performance data: H2O < 1 ppm; O2 < 1 ppm; vacuum < 0,03 mbar; circulation circulation rate > 18 m3/h; control unit: PLC control panel + manual control circulating vacuum; built-in oil vacuum pump: min 12 m3/h capacity, 2-stage, with oil filter; antechamber: manual discharge, ball valve closing, HEPA filter; - H2O and O2 sensors: PLC
Phoenix Standalone Flow Reactor	The Phoenix Standalone Continuous Flow Reactor is a highly versatile reactor for all areas of chemistry, from the simplest organic preparations to complex catalytic processes involving multiple gases (hydroformylation with H2/CO gas mixture). It is suitable for both homogeneous and heterogeneous catalytic reactions. The parameters affecting the reactions (temperature, pressure, catalyst, active field size, flow rate, etc.) can be varied over a wide range.	Phone: +36 (30) 358-7385 Other contact: Szakácsi János, szakacsi@belklinika.com, +36 303587385	Reactor system: ● 150 bar flow reactor unit with automatic pressure control unit ● Provides a space for heating up different amounts of solid material ● Suitable for heterogeneous reactions, but also with a tubular reactor section for homogeneous reactions. ● The reactor space should be made of stainless steel ● 400 °C operating temperature Material input unit(s) ● High pressure liquid pump, flow rate range: 1-5 mL/min ● Two external
MACH3 X-ray Diffractometer	The device is 23 years old. It is functional but not used. I do not recommend registering it as a large instrument.	Responsible: Dr. Bényei Attila Organizational unit: University of Debrecen; Faculty of Pharmacy; Dean’s office, Faculty of Pharmacy E-mail: abenyei@unideb.hu	Single crystal X-ray diffractometer with point detector and 80-400K thermostat. The instrument was purchased in 1996, is in working order, but is not currently (and is not expected to be) in use. Its further fate is not yet clear, e.g. the low temp unit or the goniometer could be used.
Analytical HPLC system with GPC/SEC controller	Integrated system for aqueous size exclusion chromatography measurements with computer control and evaluation. The instrument is suitable for the separation of molecules or particles of different molecular weights or hydrodynamic radii in small volumes (< 200 µl, but the injected volume may be less) of samples dissolved in aqueous media, and for the determination of molecular mass/size and size distribution between 200 and 100 00000 Da. The system is equipped with a variable wavelength UV-Vis and differential refractive index detector, detection can be performed simultaneously at 2 different wavelengths and refractive indices, and simultaneous fluorescence determination with external data acquisition is possible.	Responsible: Dr. Novák Levente Organizational unit: University of Debrecen; Faculty of Pharmacy; Department of Pharmaceutical Chemistry E-mail: novak.levente@science.unideb.hu Phone: +36 (52) 512-900/22384 Other contact: 22385	Max. 10 ml/min flow rate, adjustable volume injection system (up to 100 μl), thermostatted column space (from room temperature to 80 °C), UV (2 wavelengths simultaneously between 200-600 nm) and differential refractive index detectors, possibility to use up to 2 30 cm size exclusion chromatography columns, computer control and data processing.
Tri-Carb 4810 TR Liquid Scintillation analyzer	For the detection of low-activity gamma, beta and alpha radiation, suitable for the quantitative measurement of beta radiation in biological samples, as well as in environmental and synthetic samples in liquid spaces, for the identification and determination of the radiative components of samples of unknown origin.	Responsible: Dr. Nagy Noémi Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Physical Chemistry E-mail: nagy.noemi@science.unideb.hu Phone: +36 (52) 512-900/22263	High Sensitivity Counting measurement module, automated sample changer, low and high firing modes, two detector coincidence mode, luminescence correction, QuantaSmart software, built-in computer and monitor, linear 4000 channel spectrum analysis, 190 kg lead shield to ensure low background, automatic spectrum display, built-in TR-LSC (time shift) detection to minimize background while increasing sensitivity, etc... Translated with DeepL.com (free version)
Chiral-IR2X vibrational circular dichroism spectrometer	In the infrared region, the instrument offers the possibility to measure vibrational optical activity, which, together with DFT calculations, can provide information on the conformation and absolute configuration of the molecule.	Responsible: Dr. Kurtán Tibor Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Organic Chemistry E-mail: kurtan.tibor@science.unideb.hu Phone: +36 (52) 512-900/22470	Fourier Transform Vibrational Circular Circular Dichroism Spectrometer (MIR FT-VCD), Dual silicon carbide ceramic light source with two KRS5 polarizers combined with four-port interferometer and "cube-corner" mirrors, Mercury Cadmium Telluride (MCT) detector with liquid nitrogen cooling (MCT LN2 Detector), Spectral range: 4500 - 750 cm-1
chiral HPLC	In the UV-visible range, the instrument provides measurements of electronic circular dichroism spectra, which, together with DFT calculations, can provide information on the conformation and absolute configuration of the molecule. Coupled to a chiral HPLC system, stereoisomer mixtures can be analysed online.	Responsible: Dr. Kurtán Tibor Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Organic Chemistry E-mail: kurtan.tibor@science.unideb.hu Phone: +36 (52) 512-900/22470	150 W xenon light source, piezoelastic modulator (PEM), wavelength range: 163-900 nm.
J-810 ECD spektropolarimeter and coupled chiral HPLC system	In the UV-visible range, the instrument provides measurements of electronic circular dichroism spectra, which, together with DFT calculations, can provide information on the conformation and absolute configuration of the molecule. Coupled to a chiral HPLC system, stereoisomer mixtures can be analysed online	Responsible: Dr. Kurtán Tibor Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Organic Chemistry E-mail: kurtan.tibor@science.unideb.hu Phone: +36 (52) 512-900/22470	150 W xenon light source, piezoelastic modulator (PEM), wavelength range: 163-900 nm.
Analytical and Preparative HPLC Separation System	Analitikai és preparatív feladatokra alkalmas, különböző paraméterek által vezérelhető frakciószedéssel, szelepváltó rendszerrel, diódasoros és ELSD detektorokkal, kettős hurokkal rendelkező mintaadagolóval, kolonna termosztáttal, kromatográfiás munkaállomással felszerelt nagynyomású gradiensképző kromatográfiás rendszer.	Responsible: Dr. Kiss Attila Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Organic Chemistry E-mail: kiss.attila@science.unideb.hu Phone: +06 (52) 512-900/22344	The system is suitable for use as two separate units for analytical HPLC using both detectors (DAD and ELSD). The prepartate system operates at a flow rate of max 100ml/min up to 400bar pressure for a suitable column substrate. The system includes two fraction collectors for proper final product handling/collection.
Elementar Analyser	-	Responsible: Dr. Kiss Attila Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Organic Chemistry E-mail: kiss.attila@science.unideb.hu Phone: +06 (52) 512-900/22344	Elemental analyser for the determination of 4 elements from organic materials
THERMO LTQ XL ion trap mass spectrometer	-	Responsible: Dr. Kiss Attila Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Organic Chemistry E-mail: kiss.attila@science.unideb.hu Phone: +06 (52) 512-900/22344	Mass spectrometer suitable for MS and MSMS measurements in the mass range 15-4000 Da; suitable for MSn fragmentation where n= min.15; equipped with electrospray (ESI) and APCI ion sources;
Syrris Asia 220 flowchem system	The instrument is suitable for organic chemical reactions under flow chemistry conditions in chip and/or tube reactors. The reacting partners are flowed through the system under controlled conditions (temperature, pressure, velocity). In contrast to classical chemical synthesis, the steps (reaction, processing, isolation, purification) are "spatially separated" but take place simultaneously. The advantage of this method is the rapidity of the reactions, as the small volume (µL) of reactants in the reaction space is short, so the reaction is fast and side reactions are reduced, resulting in a purer product. The small amount of chemicals used makes the synthetic process safer. The continuous-flow chemical reactor system is suitable for optimizing and efficiently performing "classical" (flask synthesis) synthetic transformations and for carrying out organic chemical reactions in continuous operation.	Responsible: Dr. Juhász László Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Organic Chemistry E-mail: juhasz.laszlo@science.unideb.hu Phone: +36 (52) 512-900/22464	two-channel syringe pump (0 - 20 bar); dosing syringes (50/100 and 500/1000 ul); reagent dispenser (2 x 5 mL loop), chip reactor (250 and 1000 ul), tube reactor (4/ 16mL); solid phase reactors, heating units (-15 - 150 C and 25 - 250 C), product collector.
Bruker Avance II 500 NMR spectrometer	Avance II 500 NMR with superconducting magnet, field strength 11.75 Tesla, 1H frequency 500.13 MHz. The radiofrequency unit can pulse the sample in three frequency bands: 1H band, broadband (31P-109Ag range) and 2H frequency for stabilisation. Available probes: 5 mm TXI, 5 mm bbi, 5 mm dual (1H/13C), 10 mm BBO. Temperature control unit.	Responsible: Erdődiné Kövér Katalin Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Inorganic and Analytical Chemistry E-mail: kover@science.unideb.hu	Avance II 500 NMR with 11.75 Tesla superconducting magnet
ITC200 Isothermal Titration Microcalorimeter	-	Responsible: Dr. Batta Gyula Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Organic Chemistry E-mail: batta@unideb.hu Phone: +06 (52) 512-900/22234	Operating Temperature Range 2°C to 80°C Response Time 10 seconds Cell Design 200 μl, coin-shaped, Cell Material Hastelloy Alloy C-276 Titration Syringe 40 μl Maximum Usable Volume 38 μl Stirring Rate 500 to 1500 rpm
MICROCAL VP-CAPILLARY DSC microcalorimeter SYS12904	The differential scanning microcalorimetry method is based on the measurement of the thermal effect of unimolecular reactions. The DSC method does not require any labelling technique and native biomolecules can be scanned. The uncoiling (uncoiling) and denaturation of proteins, nucleic acids is accompanied by a thermal or enthalpic change. The temperature dependence of enthalpy provides information on the macroscopic states of the system, using the specific heat of Cp measured in the DSC experiment. Measurement of the heat generated during denaturation at constant pressure gives the enthalpy of the process. The DSC measures the heat capacity of the protein in aqueous medium as a function of temperature and the enthalpy of deposition can be calculated from the area under the heat capacity curve. The temperature corresponding to the Cp maximum is the "melting point", when the ratio of native to deposited populations is 50-50%. A decreasing value of Tm indicates a decrease in stability. F	Responsible: Dr. Batta Gyula Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Organic Chemistry E-mail: batta@unideb.hu Phone: +06 (52) 512-900/22234	The device is suitable for the characterization of proteins, DNA stability, thermodynamic characterization. Analysis of protein structure and protein ligand binding. ● Measurement parameters: mean temperature Tm, enthalpy ∆H, heat capacity ● Volumes:Sample volume < 400uL ● Measuring cell material: tantalum, design: capillary ● Noise level: 0.05uCal/°C ● Sample concentration: < 0.2 mg/mL ● Temperature: measuring range minimum, -10 °C ... +130°C, computer control and software evaluation
Analytical HPLC system with CoronaCAD connection	- The HPLC instrument has become a staple of analytical instrumentation, capable of solving a wide range of completely different analytical tasks by combining the right liquid transport and detection capabilities. The instrument is mainly used for enzyme characterisation, kinetic analysis, HPLC product analysis measurements. The analysis of various natural and synthetic substrates and products containing chromophore groups requires the use of two different detectors. Spectral imaging is often necessary for the identification of products, which can be achieved with the diode array detector. In addition, natural substrates and their products can only be analysed with a general detector (CoronaCad), which is available. A pump allowing gradient elution is provided for the separation of substances that often have substantially different sizes and polarities. For these purposes, a quaternary pump, a DAD detector, an external detector with connection possibility for serial measurements, an au	Responsible: Dr. Gyémánt Gyöngyi Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Inorganic and Analytical Chemistry E-mail: gyemant@science.unideb.hu	Complete HPLC system, which includes: - Four-channel, gradient pump, degasser, seal washer - automatic sample feeder with needle washing and sample space cooling - Column thermostat (30-80 oC) - diode array detector (200-640 nm, peak purity analysis, spectral recording capability) - Corona CAD detector - communication interface to control and receive Corona CAD signal - chromatography workstation (PC, monitor, printer, operating system) - controller, data processor,
Cyclic voltammetry instrument‎	The instrument includes the potentiostat, galvanostat unit, cell stand, Teflon cell sheet for electrode storage and as standard equipment glass-carbon and platinum electrodes and counter-electrode, Ag/AgCl reference electrode and accessories for basic electrochemical measurements. For further additional analysis it is possible to add a dropping mercury electrode. The apparatus is suitable for electrochemical analysis of small (min. 0,2 cm3) and large (5-15 cm3) volume samples in dilute aqueous and non-aqueous media, for recording cyclic voltammetric curves over a wide voltage range, for data evaluation, for determination of electrochemical parameters.	Responsible: Dr. Kállay Csilla Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Inorganic and Analytical Chemistry E-mail: kallay.csilla@science.unideb.hu Phone: +06 (52) 512-900/22373	The measuring equipment is open, allowing easy access to the components. The measuring equipment units (cell, mixing unit) are easy to replace and easy to clean The cell can be directly connected to other BASi electrochemical controllers (e.g. electrochemical analysers) Voltage range: 100-240 V, 50/60 Hz Power: 10 Watt Main fuse: 2,0 A Inlet gas pressure: up to 5 psi Size: 7.25" (18 cm) wide x 9.25" (23 cm) deep x 11.5" (29 cm) high Weight 10.5 lbs (5 kg)
Bruker Avance 360 MHz NMR	The instrument can perform one and two-dimensional multinuclear NMR measurements.	Responsible: Dr. Bányai István Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Physical Chemistry E-mail: banyai.istvan@science.unideb.hu Phone: +36 (52) 512-900/22384	High-resolution multinuclear magnetic resonance (NMR) instrument. It is equipped with a QNP (15N,13C, 31P and 1H) and an inverse broadband gradient probe. It is equipped with temperature adjustable probes.
Bruker Avance 400 MHz NMR	The instrument can perform one and two-dimensional multinuclear NMR measurements.	Responsible: Dr. Bányai István Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Physical Chemistry E-mail: banyai.istvan@science.unideb.hu Phone: +36 (52) 512-900/22384	High-resolution multinuclear magnetic resonance (NMR) instrument. It is equipped with a BB 10 mm and an inverse broadband gradient probe. It is equipped with temperature adjustable probes.
X-ray spectrometer	The spectrometer consists of an openable roof, a beam lock, a measuring chamber, a removable sample tray and sample holders. The X-ray elements in the low-energy range (Na, K, Al, Si, Cl, P, S) can be analysed in a vacuum or helium atmosphere. The range of elements that can be measured covers 80 elements from sodium (Z=11) to uranium (Z=92).	Responsible: Baranyai Edina Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Inorganic and Analytical Chemistry E-mail: baranyai.edina@science.unideb.hu Phone: +36 (20) 573-2937/22426	The spectrometer is equipped with a low-power side-window Rh anode X-ray tube controlled by software. The X-ray tube has a power of max 30kV and min 4kV accelerating voltage and max 9 W tube power. The tube current is min 1uA and max 1mA. The 12 sample positions sample changer provides a sample rotation (spinner). The detector is a high resolution Si-PiN diode (250eV 5,9keV), thermoelectric cooled, fully sealed.
Mass spectrometer	The equipment is a state-of-the-art high-performance, high-resolution ESI-q-TOF mass spectrometer. Electrospray ionisation (ESI) offers the possibility to study the structure of high molecular weight, non-volatile biomolecules and synthetic polymers. With the tandem q-TOF mass analyser, high-resolution MS/MS measurements can be performed, enabling the elucidation of new reaction mechanisms, the solution of complex chemical problems and the accurate determination of chemical structure.	Responsible: Dr. Gáspár Attila Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Inorganic and Analytical Chemistry E-mail: gaspar@science.unideb.hu Phone: +36 (52) 512-900/22400	The mass spectrometer is equipped with an ultra-high resolution, quadrupole (q) and time-of-flight (TOF) analyser, making it suitable for accurate mass determination in both MS and MS/MS modes. The instrument is equipped with Apollo II ESI electrospray ion source, dual ion funnel optics, high performance hyperbolic quadrupole, quadrupolar impact cell with high precision linear DC gradient. Mass resolution of 80 000 (FSR, 400-3000 m/z range) 50 Hz data acquisition
Capillary electrophoresis	In an electrolyte in a thin quartz capillary, the high electric field forces allow the different components to be separated by charge, size and shape.	Responsible: Dr. Gáspár Attila Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Inorganic and Analytical Chemistry E-mail: gaspar@science.unideb.hu Phone: +36 (52) 512-900/22400	The capillary space can be thermostated between 10-60 °C so that the heat generated does not affect the separation. Samples can be introduced into the capillary by hydrodynamic or electrokinetic injection. The applied voltage is up to +/- 30 kV. Detection is performed through the CE capillary with a built-in diode array spectrophotometer (190-600 nm), but simultaneous detection by fluorescence, laser-induced fluorescence and mass spectrometry is also possible.
Solid phase protein synthesizer‎	The Liberty1 is a fully automated microwave protein synthesizer. The device is capable of stepwise construction of peptides from amino acid building blocks automatically in Fmoc or Boc solid phase reactions. The instrument is controlled by a computer, which uses PepDriver software to control the synthesizer. The Liberty synthesizer operates with a Discover-type microwave unit, which uses optical fibre temperature measurement to precisely control and monitor the efficiency of the microwave energy. The resin and reagents are properly mixed by bubbling low pressure nitrogen while the microwave is being used. The apparatus is equipped with 20 125 ml amino acid vessels, the amino acid solutions are delivered to the reaction vessel by nitrogen or argon pressure. All amino acid, activator and TFA solutions are added using a defined volume sample loop for precise liquid delivery. The standard 30 ml Teflon reaction vessel is available in 0,1 and 0,5 mmo	Responsible: Dr. Kállay Csilla Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Inorganic and Analytical Chemistry E-mail: kallay.csilla@science.unideb.hu Phone: +06 (52) 512-900/22373	Scale of synthesis: 0,025 - 5 mmol Temperature measurement: in situ, optical fibre Heat source: microwave Liquid volume measurement: variable sample loop size and time-based liquid flow measurement Reagent delivery: nitrogen or argon pressure Residual solvent tank: 20 l storage can with overflow sensor Control unit: user's choice of laptop or desktop computer with wireless option Power supply: 120V/60Hz or 240V/50Hz. Dimensions: Width: 26 inch ( 66 cm) x Depth: 20.5 i
Semi preparative hplc‎	The semi-preparative HPLC instrument consists of small units manufactured by Jasco. The instrument allows the separation of different substances and their collection by fractionation. An important part of the instrument is the column where the separation takes place. The two solvents used are usually an aqueous and an organic solvent, in the case of the above-mentioned instrument mostly water and acetonitrile containing 0,1 % trifluoroacetic acid. The instrument is equipped with a manual injector, the injection volume to be used ranges from 100 to 250 l. The liquid phase is delivered by a double piston solvent transfer system, the pump. The two liquids delivered by the pump are mixed by the mixer in the predetermined ratio. The ideal flow rate used in the instrument is 5,0 ml/min. Degassing of the solvent is performed by the degasser. The liquid phase and the injected sample are transferred by the pump at the set flow rate to the column where the compounds are separated. The separated	Responsible: Dr. Kállay Csilla Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Inorganic and Analytical Chemistry E-mail: kallay.csilla@science.unideb.hu Phone: +06 (52) 512-900/22373	Pump: PU-2086 Plus Pump type:Double piston type Flow rate: 1 l/min - 20.0 ml/min Maximum applicable pressure: 50 MPa Detector: UV-2077 Plus Optical arrangement: single-beam photometer Polychromator: flat field type PDA: 35 channels Wavelength range: 200-600 nm Light source: deuterium lamp Photometric method: single-beam photometer Detector: 36 element photodiode Response time: 3 Mixer: MX-2080-32 Product name: Dynamic mixer Max pressure: 35 MPa Number of inputs: 3 Operating temperature
Capillary electrophoresis	In an electrolyte in a thin quartz capillary, the high electric field forces allow the different components to be separated by charge, size and shape.	Responsible: Dr. Gáspár Attila Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Inorganic and Analytical Chemistry E-mail: gaspar@science.unideb.hu Phone: +36 (52) 512-900/22400	The capillary space can be thermostated at between 10-60 °C so that the heat generated does not affect the separation. Samples can be injected into the capillary by hydrodynamic or electrokinetic injection. The applied voltage is up to +/- 30 kV. Detection is performed through the CE capillary with a built-in diode array spectrophotometer (190-600 nm), but simultaneous detection by fluorescence, laser-induced fluorescence and mass spectrometry is also possible.
SPECTROMETER STOPPED FLOW	The stopped-flow method uses a special methodology (acceleration of mixing) to monitor reactions with half-lives of less than 10 s. In the stopped-flow method, measurements are most often made spectrophotometrically after the flow of the mixed mixture has stopped abruptly. The reagents are initially placed in syringes, from which a piston, typically at a pressure of 6-8 bar, is used to combine and mix the solutions in a turbulent mixing cell through a tube system. The mixture is then transferred to the reaction cell and then to the stop syringe. A pressure switch is then closed, signalling the end of the mixing phase, at which point the pressure and hence the flow ceases and detection begins. The dead time is typically 1-3 ms.	Phone: +36 (30) 358-7385 Other contact: Szakácsi János, szakacsi@belklinika.com, +36 303587385	Monitoring of reactions occurring in 10–2 – 102 s - conventional (2 reactants) and sequential mixing (reaction of an in situ generated intermediate with a reactant) - conventional, diode array or fluorescence detection - software for fitting and evaluation of kinetic curves - variable path length (2 mm to 10 mm) - wavelength range ~200-650 nm - temperature range ~10-50 °C
Laser Flash Photolysis Spectrometer	In flash photolysis, a short pulse of light emits photons that are absorbed by molecules or ions. The resulting excited-state particles lose energy through fluorescence, non-radiative relaxation or chemical changes resulting in free radicals and other high-energy species. A pulsed laser thus produces a transient particle, whose fate can typically be monitored by absorption or fluorescence, even on a ns time scale. In absorption detection, the light source is a xenon lamp with a light path perpendicular to the laser pulse.	Phone: +36 (30) 358-7385 Other contact: Szakácsi János, szakacsi@belklinika.com, +36 303587385	- 1064 nm base wavelength laser with frequency multiplying crystals (532, 355, 266 and 213 nm) - absorption or fluorescence detection - monitoring of ns timescale processes using an oscilloscope - detection light source: xenon lamp
Ion-trap GC/MS instrument	The instrument is a standard capillary gas chromatograph equipped with an FID detector and an ion trap mass spectrometer detector. Sampling is performed by an automatic sampler with robotic arm.	Responsible: Dr. Lázár István Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Inorganic and Analytical Chemistry E-mail: lazar@science.unideb.hu Phone: +36 (52) 512-900/22376	Capillary gas chromatograph with FID detector and mass spectrometer detector.
Gas chromatograph	The instrument is a standard capillary gas chromatograph equipped with an FID detector. Sampling is performed by an approved automatic sampler.	Responsible: Dr. Lázár István Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Inorganic and Analytical Chemistry E-mail: lazar@science.unideb.hu Phone: +36 (52) 512-900/22376	capillary gas chromatograph with FID detector
AVANCE NEO 700 MHz NMR spectrometer	Modern Nuclear Magnetic Resonance (NMR) spectroscopy is, among many other applications in materials science, a very powerful tool for studying the solution structure, the dynamics of molecules and molecular interactions. Through the study of the interactions responsible for molecular recognition at the atomic level, it provides crucial information for the elucidation of structure-activity relationships and thus for the development of new therapeutics. A 700 MHz NMR spectrometer with a highly sensitive, cooled probe head allows the detection of biologically active substances that are usually available in small quantities and often have limited stability. The detection limit for small molecule-macromolecule interactions is also significantly reduced and the "macromolecule" can be a cell or a virus. The high sensitivity also offers the potential for new molecular biology studies, e.g. "cell-to-cell NMR", identification of metabolites (metabol	Responsible: Erdődiné Kövér Katalin Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Chemistry; Department of Inorganic and Analytical Chemistry E-mail: kover@science.unideb.hu	16.4 Tesla actively shielded standard bore (54 mm) superconducting magnet with 700 MHz 1H frequency. Precision digital phase, amplitude and frequency generation for three channels. Temperature adjustability: +/-0.1 ºC. Temperature stability in the range 0-50 °C <+/-0.01 °C for a 1 °C change in room temperature. Temperature range: -200 °C to 400 °C. 2 linear broadband amplifiers (frequency range 6 to 365 MHz), 500 W. 1 1H/19F linear broadband amplifier, 100 W. 1 2H linear
DOUBLE CHANEL IONCHROMATIC SYSTEM	The Dionex ICS-5000+ dual-channel ion chromatograph is capable of qualitative and quantitative determination of anions and cations simultaneously from a given sample. The measuring system consists of the following sub-assemblies: dual-channel pump, column space, automatic sample introduction unit, conductivity detector, UV-visible detector, electrochemical detector, evaluation software and computer. The use of three detectors with different characteristics allows the analysis of a fairly wide spectrum of samples with high sensitivity.	Phone: +36 (30) 358-7385 Other contact: Szakácsi János, szakacsi@belklinika.com, +36 303587385	Flow rate range: analytical: 0.000-10.000 ml/min flow rate, capillary: 0.001-0.100 ml/min flow rate Pressure range: analytical: 0-35 MPa (0-5000 psi), capillary: 0-41 MPa (0-6000 psi) Sample holder temperature control for heat sensitive samples, precisely adjustable between 4-60°C Temperature accuracy: ± 0.5°C Temperature stability: ± 0.2°C
MODULAR ION CHROMATOGRAPHY	-	Phone: +36 (30) 358-7385 Other contact: Szakácsi János, szakacsi@belklinika.com, +36 303587385	Out of service
AUTOKLÁV 8 STE AZTECA A-6612 CHAMBER 2 Door	High temperature sterilization equipment with saturated steam overpressure	Responsible: Dr. Várkonyi István Zsolt Organizational unit: Kenézy Gyula Egyetemi Kórház; Főigazgatóság; Fekvőbeteg szakellátásért felelős Igazgatóság; Központi ellátó egységek, központi egységek; Infektológiai Intézet E-mail: varkonyi.istvan@kenezy.unideb.hu Phone: +36 (52) 511-853	MSZ EN ISO 9001:2009 (ISO 9001:2008)
AUTOKLÁV 8 STE_ AZTECA A-6612 CHAMBER 2 Door	High-temperature sterilization equipment with saturated steam overpressure	Responsible: Dr. Várkonyi István Zsolt Organizational unit: Kenézy Gyula Egyetemi Kórház; Főigazgatóság; Fekvőbeteg szakellátásért felelős Igazgatóság; Központi ellátó egységek, központi egységek; Infektológiai Intézet E-mail: varkonyi.istvan@kenezy.unideb.hu Phone: +36 (52) 511-853	MSZ EN ISO 9001:2009 (ISO 9001:2008)
AUTOKLÁV 8 STE AZTECA A-6612 CHAMBER 2 Door	High temperature sterilization equipment with saturated steam overpressure	Responsible: Dr. Várkonyi István Zsolt Organizational unit: Kenézy Gyula Egyetemi Kórház; Főigazgatóság; Fekvőbeteg szakellátásért felelős Igazgatóság; Központi ellátó egységek, központi egységek; Infektológiai Intézet E-mail: varkonyi.istvan@kenezy.unideb.hu Phone: +36 (52) 511-853	MSZ EN ISO 9001:2009 (ISO 9001:2008)
AUTOKLÁV 8 STE AZTECA A-6612 CHAMBER 2 Door	High temperature sterilization equipment with saturated steam overpressure	Responsible: Dr. Várkonyi István Zsolt Organizational unit: Kenézy Gyula Egyetemi Kórház; Főigazgatóság; Fekvőbeteg szakellátásért felelős Igazgatóság; Központi ellátó egységek, központi egységek; Infektológiai Intézet E-mail: varkonyi.istvan@kenezy.unideb.hu Phone: +36 (52) 511-853	MSZ EN ISO 9001:2009 (ISO 9001:2008)
Amsco V-PRO maX	Low temperature sterilization equipment using H2O2.	Responsible: Dr. Várkonyi István Zsolt Organizational unit: Kenézy Gyula Egyetemi Kórház; Főigazgatóság; Fekvőbeteg szakellátásért felelős Igazgatóság; Központi ellátó egységek, központi egységek; Infektológiai Intézet E-mail: varkonyi.istvan@kenezy.unideb.hu Phone: +36 (52) 511-853	MSZ EN ISO 9001:2009 (ISO 9001:2008)
Amsco V-PRO maX	Low temperature sterilization equipment using H2O2.	Responsible: Dr. Várkonyi István Zsolt Organizational unit: Kenézy Gyula Egyetemi Kórház; Főigazgatóság; Fekvőbeteg szakellátásért felelős Igazgatóság; Központi ellátó egységek, központi egységek; Infektológiai Intézet E-mail: varkonyi.istvan@kenezy.unideb.hu Phone: +36 (52) 511-853	MSZ EN ISO 9001:2009 (ISO 9001:2008)
Water Softener Equipment	Preparation and delivery of soft water to the required equipment.	Responsible: Dr. Várkonyi István Zsolt Organizational unit: Kenézy Gyula Egyetemi Kórház; Főigazgatóság; Fekvőbeteg szakellátásért felelős Igazgatóság; Központi ellátó egységek, központi egységek; Infektológiai Intézet E-mail: varkonyi.istvan@kenezy.unideb.hu Phone: +36 (52) 511-853	MSZ EN ISO 9001:2009 (ISO 9001:2008)
CELLAVISION DM 1200	It allows automatic evaluation of blood and body fluid smears, suitable for remote evaluation and consultation.	Responsible: Tóth Gábor Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Diagnostic Units; Laboratory Medicine E-mail: tothg@med.unideb.hu Phone: +36 (30) 360-2516	Size dimensions: 58x45x71 cm, weight 80 kg, power: 500 W
SYNERGIE PEARLS	BY CIRCULATING THE FLUIDISATION FILLER, IT PREVENTS THE FORMATION OF BLOATING	Responsible: Bojti Mihályné Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Clinics; Department of Dermatology E-mail: bojtine@med.unideb.hu Phone: +36 (52) 411-600/54527 Other contact: DR. PATÓCS LÁSZLÓ, PATOCSL@PRO-KLINIMED.HU, 0626-390-441	SAND BED - INTEGRATED HEATING-COOLING SYSTEM WITH CONTROL UNIT, AIR FILTERS, INTEGRATED STERILISATION UNIT HEIGHT 90-120CM, WEIGHT 150KG
OEC One Mobile C-arm X-ray Product	The OEC One is a mobile C-arm imaging system consisting of a mobile stand supporting a 27" monitor and a 10.1" tablet via an articulated arm and a "C" shaped device. The C-arm contains the X-ray source assembly at the top and the image intensifier at the opposite end. The apparatus comprises: mobile C-arm, X-ray generator, collimator, image intensifier, display device, foot switch, manual switch. The monitor and tablet are touch screen. The equipment has the following functions and settings: scan control, image memory, caption, measurement, zoom, query, setting, save, exposure mode, dose data, tube temperature, image acquisition, field size change, noise filter, low dose mode, digital point mode, pulsating mode, contrast, brightness adjustment, automatic contrast/brightness, smart metal, kVp value adjustment, mA value adjustment, automatic exposure.	Responsible: Juhász Péter Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Clinics; Department of Pediatrics; General Pediatrics E-mail: juhasz.peter@med.unideb.hu Phone: +36 (30) 465-8613	Class I equipment (according to IEC60601-1), type B protection against electric shock (IEC60601-1), standard protection against water ingress, protection class: system: IPX0, footswitch: IPX8, operating mode: continuous, load mode: intermittent
CENTRAL UNIT WITH GESTURE CONTROL	-	Responsible: Grezsuné Kenyeres Ildikó Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Clinics; Department of Surgery E-mail: kenyeres.ildiko@med.unideb.hu Phone: +36 (30) 256-9842	SPECIAL LAPAROSCOPIC TOWER TROLLEY, 43", TOWER-MOUNTED GESTURE-CONTROLLED 5K VERTICAL RESOLUTION, CAPABLE OF RECEIVING USB CONNECTION, INTERNET CONNECTIVITY, COMPUTER-BASED IMAGE PROCESSING AND STORAGE, LOW TEMPERATURE 45˚C LED LIGHT SOURCE, INTEGRATED IMAGE-VIDEO RECORDING CAPABILITY FROM CAMERA HEAD, WEB INTERFACE CONNECTIVITY, INTEGRATED WITH CAMERA AND LIGHT CABLE, 10 mm 30 DEGREES, WITH AUTOMATIC OVERPRESSURE SENSOR, WITH IN-LINE FILTER
CENTRAL UNIT WITH GESTURE CONTROL	-	Responsible: Grezsuné Kenyeres Ildikó Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Clinics; Department of Surgery E-mail: kenyeres.ildiko@med.unideb.hu Phone: +36 (30) 256-9842	SPECIAL LAPAROSCOPIC TOWER TROLLEY, 43", TOWER-MOUNTED GESTURE-CONTROLLED 5K VERTICAL RESOLUTION, CAPABLE OF RECEIVING USB CONNECTION, INTERNET CONNECTION, COMPUTER-BASED IMAGE PROCESSING AND STORAGE, LOW TEMPERATURE 45˚C LED LIGHTING, INTEGRATED IMAGE VIDEO RECORDING OPPORTUNITY FROM CAMERA PANEL, WEBSITE CONFIGURABLE,EQUIPPABLE WITH CAMERA AND PHOTO PANEL,10 millimetres 30 degrees
CUSA EXL9	CUSA EXEL SYSTEM IS AN UH SURGICAL ASPIRATOR, THAT ALLOWS THE SURGEON TO REMOVE TISSUE SELECTIVELY AND WITH HIGH PRECISION.	Responsible: Grezsuné Kenyeres Ildikó Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Clinics; Department of Surgery E-mail: kenyeres.ildiko@med.unideb.hu Phone: +36 (30) 256-9842	3 FUNCTIONS: - FRAGMENTATION -DISPLAY -ASPIRATION
HEIDELBERG ENGINEERING GmbH	Optical coherence tomograph for examination and measurement of the anterior segments of the eye.	Responsible: Nagy Zoltán Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Clinics; Department of Ophthalmology E-mail: znagy@med.unideb.hu Phone: +36 (30) 830-1171	Optical coherence tomograph.
C-arc image intensifier	GE OEC Elite C-arc CFD technology scanner with vascular function 9"	Responsible: Jasákné Hricz Mária Organizational unit: University of Debrecen; University of Debrecen Clinical Centre; Health Care Service Units; Clinics; Department of Internal Medicine; Internal Medicine Clinic, Building A E-mail: hricz.maria@med.unideb.hu	2.2 kw power, 2 focal points, 3 adjustable image sizes, 40 mA fluoroscopy, pulse mode, dose reduction mode, 27" TFT-LCD screen, 1Kx1K image display matrix, automatic contrast and brightness control, iron curtain function with Cine mode, DSA function.
Autoklav	The equipment is suitable for sterilising heat-tolerant equipment, instruments and bandages.	Responsible: Horváth Éva Organizational unit: Klinikai Központ; Fogorvosi járó- és fekvőbeteg alap- és szakellátó szolgálat E-mail: horvath.eva@dental.unideb.hu Phone: +36 (70) 341-0134	A saturated pressurized steam sterilizer with its own steam supply.
Drop Shape Analyzer	Determine the wetting parameters of surfaces, interfaces. Software-controlled two-site dispensing system with water and diiodo-metane, High-speed USB camera module, Droplet shape analysis system for contact angle measurement and surface free energy measurement of solid samples. Additional optics for the analysis of micro-sized droplets.	Responsible: Dr. Hegedűs Csaba Organizational unit: University of Debrecen; Faculty of Medicine; Institute of Medical Chemistry E-mail: hcsaba@med.unideb.hu Phone: +36 (52) 411-717/54349	high resolution USB camera module. Optical system, manual zoom (6.5x ), Dual dispenser for precise software-controlled dispensing of 2 test liquids, 1 test liquid for manual dispensing LED lighting for small contact angles max. sample size: 320x ∞ x 275 mm (WxDxH) software module for static and dynamic contact angle measurement by droplet and bubble trapping. Measuring range: 1 -180° (0,1°) Software to determine the surface free energy (SFE) of solid samples based on the measured contact angl
MCR 102 Rheometer	Depending on the sample quality and quantity (recommended sample volume: 0-2 ml) and the measuring head used, it can be used to determine flow properties, rotational and oscillatory measurements in different measuring ranges. Measuring heads are available with identification chips of different sizes, with flat-plate or cone-plate geometry, and the sample holder is temperature-controlled.	Responsible: Dr. Hegedüs Csaba Organizational unit: University of Debrecen; Faculty of Dentistry; Non-independent Department of Biomaterials and Prosthetic Dentistry E-mail: hegedus.csaba.prof@dental.unideb.hu Phone: +36 (52) 411-717/54349	Modular expandable rheometer Max. torque 180 mNm or more Min. torque (rot.) 10 nNm or less Min. torque (osc.) 10 nNm or less Torque resolution 1 nNm or less Angle of deflection 1-∞ rad or wider range Angle of deflection resolution 0,01 rad or less P-PTD200 water-cooled load cell P-PTD200/AIR air cooled load cell PP50 gauge head with flat-plate geometry CP50 cone-plate geometry probe 1o inclination PP25 gauge head with flat-plate geometry CP25 Cone-plate geometry gauge head
WES	The instrument performs automated capillary electrophoresis-based protein separation, detection (with appropriate antibody) and (relative) quantitative analysis of 12 or 24 very small volume (3 uL) samples (protein requirement: min. 0.5 ug) in parallel.	Responsible: Dr. Hegyi Zoltán Organizational unit: University of Debrecen; Faculty of Medicine; Department of Anatomy, Histology and Embryology E-mail: hegyiz@anat.med.unideb.hu Phone: +36 (52) 255-567/55441	Testable protein mass: 2-440 kDa; 3-4 log dynamic range; sensitivity in the ng range; resolution: ± 15-20% if MW <20 kDA, ± 10% if MW >20 kDa
Sorvall WX ultra ultracentrifuge	The instrument is suitable for preparative centrifugation of various complex samples. The instrument is compatible with both fixed and swing arm rotors. In addition to simple preparative centrifugation, it is also suitable for gradient centrifugation, isolation of micro-soma fractions, and purification of viruses and bacteriophages.	Responsible: Dr. Csösz Éva Organizational unit: University of Debrecen; Faculty of Medicine; Department of Biochemistry and Molecular Biology E-mail: cseva@med.unideb.hu Phone: +36 (52) 512-900/55734	Coolable rotor chamber, adjustable acceleration and braking. Rotor types: Type 35: max 35000 rpm; TFT 50.38Ti: max. 50000 rpm; Type 50: max. 40000 rpm; SW41 Ti: max. 41000 rpm; SW 55 Ti: max 55000 rpm; Type 19: max. 19000 rpm; TZT 42-650: max. 42000 rpm.
Roche Cobas Z 480Analyzer	The cobas® Z 480 system offers state-of-the-art test menu, fully automated sample preparation, real-time PCR amplification/detection and easy-to-use software for multiple sample types.	Responsible: Dr. Soltész Beáta Organizational unit: University of Debrecen; Faculty of Medicine; Department of Human Genetics E-mail: soltesz.beata@med.unideb.hu Phone: +36 (20) 455-5477/65009	RT-PCR
LICOR LI-6800F portable photosynthesis system	The LI-6800F is the latest photosynthesis measurement system, featuring easy transport, ruggedness, flexibility and highly integrated hardware and software. High-precision, robust, stable gas analysers built into the measuring head allow immediate detection of changes in the leaf without delay, even under field conditions. Environmental conditions affecting plant assimilation can be fully controlled in the sample chamber. CO2 levels, humidity, temperature and the quantity and quality of illumination can be very precisely controlled in the environment of the leaf measured surface. The actual assimilation processes in the leaf can be measured in real time with the instrument. With the integrated CO2 control system, different carbon dioxide levels can be modelled during measurements. The illumination intensity can be varied within a wide range of wavelengths. Gas exchange measurements and fluorescence measurements can be performed in parallel with the fluorescence measuring head.	Responsible: Dr. Csajbók József Organizational unit: University of Debrecen; Faculty of Agricultural and Food Sciences and Environmental Management; Institute of Crop Sciences; Department of Plant Breeding and Landscape Ecology E-mail: csj@agr.unideb.hu Phone: +36 (52) 508-465	CO2 Analyser Absolute, open path, non-dispersive infrared gas analyser. Range: 0-3100 µmol mol-1. Maximum deviation: ± 1% below 200 µmol mol-1, ± 2% above 200 µmol mol-1. H2O analyser Absolute, open path, non-dispersive infrared gas analyser. Range: 0-75 mmol mol-1. Maximum deviation: ± 1.5% at >5 mmol mol-1. Leaf chamber fluorescence meter Measurement (Modulated) light: red LED, 625 nm, software controlled intensity, software selectable modulation frequencies 1 Hz - 250 kH
ICP-OES spektrometer	Dual (radial and axial) plasma monitoring, simultaneous operation for all measurable elements. Wavelength range: min. 170-770 nm, with continuous mapping and vertically positioned flare to eliminate interferences in case of complex sample matrix. Operates with a vertical flare solution that is simple and efficient, requiring no further fine-tuning or readjustment. Glass concentric atomizer and glass cyclone fog chamber with special injector connection for easy installation and use.	Responsible: Tóth Mária Organizational unit: University of Debrecen; Faculty of Science and Technology; Institute of Biology and Ecology; Department of Ecology E-mail: toth.maria@science.unideb.hu Phone: +36 (52) 512-900/22617	PC-controlled peristaltic pump with adjustable speed to shorten flushing time and allow more cost-effective metering through reduced gas consumption. High speed automatic sample feeder. Noiseless removal of axial plasma end without compressed air by means of a cone to reduce gas consumption and eliminate interferences.
AlterG Pro 500 anti-gravity treadmill	Professional antigravity treadmill	Responsible: Kovács Csilla Organizational unit: University of Debrecen; Sports Diagnostics, Lifestyle, and Therapy Centre E-mail: kovacs.csilla@med.unideb.hu	Dimensions: length 240 cm, width 102 cm, weight 499 kg. Performance: use weight:400 lbs(182 kg), tread: 22 inches(56 cm) wide, 158 cm long. Speed range: 0-29 km/h forward, reverse:0-16 km/h.
TOP-X DR TRAUMA	Ceiling Digital X-Ray Imaging Equipment	Responsible: Kovács Csilla Organizational unit: University of Debrecen; Sports Diagnostics, Lifestyle, and Therapy Centre E-mail: kovacs.csilla@med.unideb.hu	Movable pipe support assembly, combined weight: 127 kg. FD detector weight: up to 3.6-4 kg A/D conversion min. 14-16 bits.